Evidence map›Paper›PMID 39359713›Full record

ArticleToxicology research2024

Assessment of the toxic influence of locally formulated pesticides on hepatic and renal biomarkers in male Wistar rats.

Esther Itunuoluwa Adeyele, Esther Olutomilayo Ayanyemi, Rufus Ojo Akomolafe, Olaoluwa Olukiran Sesan, Omolara Titilayo Aladesanmi, Aderonke Okoya Adetutu

Abstract read
In one paragraph

Article in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esther Itunuoluwa AdeyeleInstitute of Ecology and Environmental Studies, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0009-0006-2370-8994
Esther Olutomilayo AyanyemiInstitute of Ecology and Environmental Studies, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0009-0005-5196-1332
Rufus Ojo AkomolafeDepartment of Physiological Sciences, Faculty of Basic Medical Sciences, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0000-0001-7812-8563
Olaoluwa Olukiran SesanDepartment of Physiological Sciences, Faculty of Basic Medical Sciences, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0000-0001-5948-7982
Omolara Titilayo AladesanmiInstitute of Ecology and Environmental Studies, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0000-0001-7213-3505
Aderonke Okoya AdetutuInstitute of Ecology and Environmental Studies, Obafemi Awolowo University, Road 7, P.M.B 13, Ile Ife, Osun State, 220282, Nigeria.ORCID https://orcid.org/0000-0003-2487-4426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is growing concern of the potential damage to vital organs after long term exposure to locally formulated pesticides in rural area of Nigeria. This study was designed to assessed the effects of the individual chemical compound and their combination on the kidney and liver of rats' model. Methodology: Fifty-four rats divided into six groups and three sub-groups were exposed to 25, 50 and 75% dose of each of the pesticide's LD Conclusion: This study established that individual pesticides and their mixture is toxic to the liver and kidney, as evidenced by the elevated markers of renal and liver functions and distortion of the structure of both organs as revealed by their photomicrographs. Therefore, it is a matter of public health significance to regularly monitor pesticide residues in foods and humans in order to assess the food safety risk and population exposure to pesticides.

Indexed as

kidneylivernaphthaleneorganophosphatespesticidesrats

Identifiers

PMID39359713
PMCPMC11442146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.