Evidence map›Paper›PMID 39359331›Full record

ArticleCureus2024

Atypical Presentation of Disseminated Varicella Zoster Virus Infection Mimicking Bullous Pemphigoid.

Aleksandar Timotijevic, Andrea Boni, Marina Antic, Margaret Paulson, Erik Sviggum, Villy Yankova, Igor Dumic

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aleksandar TimotijevicDepartment of Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
Andrea BoniDepartment of Pathology, Mayo Clinic Health System, Eau Claire, USA.
Marina AnticDepartment of Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
Margaret PaulsonDepartment of Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
Erik SviggumDepartment of Radiology, Mayo Clinic Health System, Eau Claire, USA.
Villy YankovaDepartment of Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.
Igor DumicDepartment of Hospital Medicine, Mayo Clinic Health System, Eau Claire, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella-zoster virus (VZV) infection typically presents as a mild, self-limiting illness in children but can be severe and life-threatening in adults, particularly those who are immunocompromised. Atypical presentations, including hemorrhagic, necrotizing, and bullous forms, can complicate diagnosis and lead to delays in appropriate treatment. We present a case of a disseminated bullous VZV infection in an immunocompromised patient with cancer. The patient, initially misdiagnosed with bullous pemphigoid, was treated with oral steroids. The patient's condition progressed to acute respiratory distress syndrome, and she ultimately succumbed to the infection. This case underscores the importance of considering VZV as a differential diagnosis in immunocompromised patients presenting with bullous lesions. Early recognition and appropriate antiviral therapy are crucial for improving outcomes and preventing severe complications.

Indexed as

bullous pemphigoid (bp)herpes zosterimmunosuppression therapyvaricella pneumoniavaricella zoster reactivation disseminated herpes zostervzv

Identifiers

PMID39359331
PMCPMC11444743

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.