Evidence map›Paper›PMID 39359208›Full record

ArticleDiabetes, obesity & metabolism2025

Metabolic risk factor targets in relation to clinical characteristics and comorbidities among individuals with type 2 diabetes treated in primary care - The countrywide cross-sectional AUSTRO-PROFIT study.

Harald Sourij, Kehkishan Azhar, Faisal Aziz, Harald Kojzar, Caren Sourij, Peter Fasching, Martin Clodi, Bernhard Ludvik, Julia K Mader, Michael Resl and 7 more

Abstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Harald SourijInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.ORCID 0000-0003-3510-9594
Kehkishan AzharInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.ORCID 0009-0007-8941-1728
Faisal AzizInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.ORCID 0000-0002-0109-2969
Harald KojzarInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.
Caren SourijInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.
Peter FaschingDivision of Endocrinology, Rheumatology and Acute Geriatrics, Clinic Ottakring, Vienna, Austria.
Martin ClodiClinical Division of Internal Medicine, Saint John of God Hospital, Linz, Austria.
Bernhard LudvikDepartment of Internal Medicine and Karl Landsteiner Institute of Obesity and Metabolic Disorders, Landstrasse Clinic, Vienna, Austria.
Julia K MaderDivision of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.ORCID 0000-0001-7854-4233
Michael ReslClinical Division of Internal Medicine, Saint John of God Hospital, Linz, Austria.
Gersina Rega-KaunDivision of Endocrinology, Rheumatology and Acute Geriatrics, Clinic Ottakring, Vienna, Austria.
Claudia RessDepartment of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria.
Lars StechemesserDepartment of Internal Medicine I, Paracelsus Medical University, Salzburg, Austria.
Harald StinglDivision of Internal Medicine, Hospital Mödling, Mödling, Austria.
Norbert J TripoltInterdisciplinary Metabolic Medicine Trials Unit, Medical University of Graz, Graz, Austria.ORCID 0000-0002-7566-2047
Thomas WascherFirst Medical Department of Hanusch-Krankenhaus, Vienna, Austria.
Susanne KaserDepartment of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria.

Funding

Boehringer IngelheimDaiichi Sankyo EuropeMSD Sharp and DohmeNovartis PharmaNovo Nordisk Foundation Center for Basic Metabolic ResearchÖsterreichische Diabetes GesellschaftRoche Diagnostics
6 · The paper itself

Abstract

aimsThis study assessed the achievement rates of metabolic risk factor targets and their association with clinical characteristics and comorbidities among individuals with type 2 diabetes (T2D) treated in the primary care in Austria. MATERIALS AND

methodsA countrywide cross-sectional study, the AUSTRO-PROFIT, was conducted in Austria from 2021 to 2023 on 635 individuals with T2D. Metabolic risk factor targets were defined as the percentage of people achieving low-density lipoprotein cholesterol (LDL-C) <70 mg/dL (or < 55 mg/dL if cardiovascular or microvascular disease was present), glycated haemoglobin (HbA1c) <7% (53 mmol/mol) and blood pressure < 140/90 mmHg.

resultsThe mean age of the participants was 65.7 ± 11.2 years; the median duration of T2D was 8 (4-14) years; and 58.7% of the participants were male. The percentages of participants achieving LDL-C, HbA1c, blood pressure and all targets were 44%, 53%, 57% and 13%, respectively. Older age, longer T2D duration, cardiovascular disease and microvascular complications were associated with suboptimal achievement of metabolic risk factor targets.

conclusionsThe AUSTRO-PROFIT study revealed notable variations in metabolic targets achievement with respect to clinical characteristics and comorbidities. These findings underscore the importance of establishing national diabetes registries and implementing multifactorial targeted and individualized interventions to further improve the quality of T2D care in primary care settings in Austria.

Indexed as

ComorbidityDiabetes Mellitus, Type 2Glycated HemoglobinPrimary Health CareAgedAustriaBlood PressureCardiometabolic Risk FactorsCardiovascular DiseasesCholesterol, LDLCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsCholesterol, LDLGlycated Hemoglobinhemoglobin A1c protein, humanclinical characteristicscomorbiditiesmetabolic risk factor targetsprimary caretype 2 diabetestype 2 diabetes care

Identifiers

PMID39359208
PMCPMC11618246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.