Evidence map›Paper›PMID 39359110›Full record

ArticleOrthopaedic surgery2024

Effect of Different Injury Morphology of the Endplate on Intervertebral Disc Degeneration: Retrospective Cohort Study.

Qiuyu Yu, Kang Chen, Zhongyi Guo, Yaozheng Han, Lintao Su, Changyu Lei, Jun Ma, Hui Kang

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Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Qiuyu YuDepartment of Traumatic Orthopedics, Suizhou Hospital, Hubei University of Medicine, Suizhou, Hubei, China.
Kang ChenDepartment of Traumatic Orthopedics, Suizhou Hospital, Hubei University of Medicine, Suizhou, Hubei, China.
Zhongyi GuoWuhan University of Science and Technology, Wuhan, Hubei, China.
Yaozheng HanWuhan University of Science and Technology, Wuhan, Hubei, China.
Lintao SuWuhan University of Science and Technology, Wuhan, Hubei, China.
Changyu LeiWuhan University of Science and Technology, Wuhan, Hubei, China.
Jun MaGeneral Hospital of Central Theater Command, Wuhan, Hubei, China.
Hui KangGeneral Hospital of Central Theater Command, Wuhan, Hubei, China.ORCID https://orcid.org/0000-0003-1000-581X

Funding

Hubei Province health and family planning scientific research project WJ2023M091Medical Youth Top Talent Project of Hubei Province [2019]48#Postdoctoral Fund of General Hospital of Central Theater Command BSH018
6 · The paper itself

Abstract

objectivesTo describe a simplified classification scheme for endplate injury morphology based on 3D CT and to examine possible associations between endplate injury morphology and vertebral space and other variables such as type of fracture and disc degeneration in a group of patients with thoracolumbar fractures.

methodsThis study was a retrospective cohort study. We collected patients with thoracolumbar fractures admitted from January 2015 to August 2020 and divided them into three groups based on the morphology of endplate injury (45 cases of mild endplate injury, 54 cases of moderate endplate injury, and 42 cases of severe endplate injury, SEI). Data of vertebral body and intervertebral space height and angle, the Pfirrmann grade, endplate healing morphology were collected during preoperative, postoperative, and long-term follow-up of patients in each group. One-way analysis of variance (ANOVA), chi-squared test, and repeated measurement ANOVA were used to compare and analyze the influence of endplate injury morphology on patient prognosis.

resultsMost moderate injuries to the endplate (fissure-type injury) and severe injuries (irregular depression-type injury, Schmorl's node-type injury) resulted in significant disc degeneration in the long-term transition. This study also showed significant differences in the height of the anterior margin of the injured spine and the intervertebral space height index during this process.

conclusionsThe current study suggests that although the region of injury in endplate fissure-type injury is small preoperatively, it may be a major factor in leading to severe disc degeneration, loss of intervertebral height, and Cobb angle in the long term. The results of our study therefore may allow surgeons to predict the prognosis of patients with thoracolumbar fractures and guide their treatment.

Indexed as

Intervertebral Disc DegenerationLumbar VertebraeSpinal FracturesThoracic VertebraeAdultAgedCohort StudiesFemaleHumansImaging, Three-DimensionalMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedYoung Adultendplateinjury morphologyintervertebral disc degenerationspinal fracturesthoracolumbar fracture

Identifiers

PMID39359110
PMCPMC11608786

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.