Evidence map›Paper›PMID 39358959›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2024

PAD4 Inhibitor-Loaded Layered Double Hydroxide Nanosheets as a Multifunctional Nanoplatform for Photodynamic Therapy-Mediated Tumor Metastasis Treatment.

Rong Chen, Tingting Hu, Yu Lu, Shuqing Yang, Min Zhang, Chaoliang Tan, Ruizheng Liang, Yuji Wang

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Advanced Therapeutic Approach Based on LDHs-Mimetic Oxidoreductase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  8. Article
  9. Target neutrophil heterogeneity and plasticity in cancer.Journal of hematology & oncology · 2025
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rong ChenDepartment of Medicinal Chemistry, College of Pharmaceutical Sciences of Capital Medical University, Beijing, 100069, P. R. China.
Tingting HuDepartment Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, 999077, P. R. China.
Yu LuDepartment of Medicinal Chemistry, College of Pharmaceutical Sciences of Capital Medical University, Beijing, 100069, P. R. China.
Shuqing YangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.
Min ZhangDepartment of Nephrology, Affiliated Beijing Chaoyang Hospital of Capital Medical University, Beijing, 100020, P. R. China.
Chaoliang TanDepartment Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, 999077, P. R. China.ORCID 0000-0003-1695-5285
Ruizheng LiangState Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, 100029, P. R. China.
Yuji WangDepartment of Medicinal Chemistry, College of Pharmaceutical Sciences of Capital Medical University, Beijing, 100069, P. R. China.

Funding

Beijing Hospitals Authority Clinical Medicine Development ZLRK202308Chinese Institutes for Medical Research, BeijingFundamental Research Funds for the Central Universities XK1803-05National Natural Science Foundation of China 22288102National Natural Science Foundation of China-Excellent Young Scientists Fund 52122002National Natural Science Foundation of China-Excellent Young Scientists Fund 52322317Organized Scientific Research Program CX23YZ06
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is demonstrated to be effective in inducing antitumor immune responses for tumor metastasis treatment. However, tumor hypoxia, inferior tissue penetration of light, and low singlet oxygen (

Indexed as

HydroxidesNeoplasm MetastasisPhotochemotherapyAnimalsCell Line, TumorHumansMiceNanoparticlesNanostructuresProtein-Arginine Deiminase Type 4HydroxidesProtein-Arginine Deiminase Type 4immunogenic cell deathimmunotherapylayered double hydroxidesphotodynamic therapytumor metastasis

Identifiers

PMID39358959
PMCPMC11636073

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.