Evidence map›Paper›PMID 39358836›Full record

Trial reportPhysiological reports2024

The effect of home-based neuromuscular electrical stimulation-resistance training and protein supplementation on lean mass in persons with spinal cord injury: A pilot study.

Sven Hoekstra, James A King, Jordan Fenton, Natasha Kirk, Scott A Willis, Stuart M Phillips, Nick Webborn, Keith Tolfrey, Johan De Vogel-Van Den Bosch, Vicky L Goosey-Tolfrey

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sven HoekstraPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
James A KingSchool of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Jordan FentonPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Natasha KirkPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Scott A WillisSchool of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Stuart M PhillipsDepartment of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
Nick WebbornPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Keith TolfreyPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.
Johan De Vogel-Van Den BoschDanone Research and Innovation, Utrecht, The Netherlands.
Vicky L Goosey-TolfreyPeter Harrison Centre for Disability Sport, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire, UK.ORCID 0000-0001-7203-4144

Funding

Danone Foundation 2021-07
6 · The paper itself

Abstract

In persons with a spinal cord injury (SCI), resistance training using neuromuscular electrical stimulation (NMES-RT) increases lean mass in the lower limbs. However, whether protein supplementation in conjunction with NMES-RT further enhances this training effect is unknown. In this randomized controlled pilot trial, 15 individuals with chronic SCI engaged in 3 times/week NMES-RT, with (NMES+PRO, n = 8) or without protein supplementation (NMES, n = 7), for 12 weeks. Before and after the intervention, whole body and regional body composition (DXA) and fasting glucose and insulin concentrations were assessed in plasma. Adherence to the intervention components was ≥96%. Thigh lean mass was increased to a greater extent after NMES+PRO compared to NMES (0.3 (0.2, 0.4) kg; p < 0.001). Furthermore, fasting insulin concentration and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) were decreased similarly in both groups (fasting insulin: 1 [-9, 11] pmol∙L

Indexed as

Body CompositionElectric Stimulation TherapyResistance TrainingSpinal Cord InjuriesAdultBlood GlucoseDietary ProteinsDietary SupplementsFemaleHumansInsulinInsulin ResistanceMaleMiddle AgedMuscle, SkeletalPilot ProjectsBlood GlucoseDietary ProteinsInsulinexercise trainingmuscle massparalysisrehabilitationwhey protein

Identifiers

PMID39358836
PMCPMC11446856

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.