Evidence map›Paper›PMID 39358760›Full record

ArticleVirology journal2024

Genomic analysis of an acute gastroenteritis outbreak caused by rotavirus C in Hebei, China.

Kaiying Wang, Yun Wang, Lang Yang, Jinhui Li, Peihan Li, Chaojie Yang, Leili Jia, Shaofu Qiu, Hongbin Song, Peng Li

Abstract read
In one paragraph

Article in Virology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kaiying Wang *Chinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Yun Wang *Tianjin Binhai New Area Center for Disease Control and Prevention, Tianjin, 300450, China.
Lang Yang *Chinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Jinhui LiChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Peihan LiChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Chaojie YangChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Leili JiaChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China.
Shaofu QiuChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China. qiushf0613@hotmail.com.
Hongbin SongChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China. hongbinsong@263.net.
Peng LiChinese PLA Center for Disease Control and Prevention, 20 Dongda Street, Fengtai District, Beijing, 100071, China. jiekenlee@126.com.

Funding

National Key Research and Development Program of China 2023YFC2604400National Science and Technology Major Project 2018ZX10305410
6 · The paper itself

Abstract

Rotavirus group C is an important cause of sporadic cases and outbreaks of gastroenteritis worldwide. Whole-Genome sequences of human rotavirus C (RVC) in public databases are limited. We performed genome sequencing to analyze a RVC outbreak of acute gastroenteritis in China. Samples from 22 patients were screened for pathogens using RT-PCR, and six samples were positive for rotavirus. Whole-Genome sequencing analysis showed that the outbreak strain SJZ217 belongs to the G4-P[2]-I2-R2-C2-M3-A2-N2-T2-E2-H2 genotype and shares almost identical genomic sequences with Chungnam isolated in Korea. Phylogenetic analysis revealed strain SJZ217 also fell into a cluster with rotavirus C strains from Japan and Europe. Reassortment in the VP4 fragment was observed. These results helped to understand the genetic diversity and possible spread of RVC strains.

Indexed as

Disease OutbreaksGastroenteritisGenome, ViralGenotypePhylogenyRotavirusRotavirus InfectionsChild, PreschoolChinaCluster AnalysisFemaleGenetic VariationHumansInfantMaleReassortant VirusesRNA, ViralGenetic recombinationHuman rotavirus CPhylogenetic analysis

Identifiers

PMID39358760
PMCPMC11448206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.