Evidence map›Paper›PMID 39358718›Full record

ArticleBMC gastroenterology2024

Surgical treatment of chronic pancreatitis with an inflammatory pancreatic head mass: a retrospective study.

Michael Rousek, Pavel Záruba, Jiří Pudil, Eliška Kšírová, Radek Pohnán

Abstract read
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Michael RousekDepartment of Surgery, Second Faculty of Medicine of Charles University, Military University Hospital, Prague, Czech Republic. michael.rousek@uvn.cz.
Pavel ZárubaDepartment of Surgery, Second Faculty of Medicine of Charles University, Military University Hospital, Prague, Czech Republic.
Jiří PudilDepartment of Surgery, Second Faculty of Medicine of Charles University, Military University Hospital, Prague, Czech Republic.
Eliška KšírováDepartment of Bioinformatics, Second Faculty of Medicine of Charles University, Prague, Czech Republic.
Radek PohnánDepartment of Surgery, Second Faculty of Medicine of Charles University, Military University Hospital, Prague, Czech Republic.

Funding

Ministerstvo Obrany České Republiky MO 1012
6 · The paper itself

Abstract

backgroundConservative treatment of chronic pancreatitis has only a limited effect in most patients. Surgery offers very good long-term results, even in the early stages of the disease. Unfortunately, only a minority of patients undergo surgical treatment. The aim of this work was to summarise the current treatment options for patients with an inflammatory mass of the pancreatic head. Data from patients in our study demonstrates that the surgery is a safe method, and here we compare the perioperative and early postoperative outcomes of patients who underwent a pancreatoduodenectomy and duodenum-preserving pancreatic head resection for chronic pancreatitis.

methodsAll patients who underwent a pancreaticoduodenectomy or a duodenum-preserving pancreatic head resection in our department between 2014 and 2022 were included in this study. Perioperative and early postoperative results were statistically analysed and compared.

resultsThirty-eight pancreaticoduodenectomies and 23 duodenum-preserving pancreatic head resections were performed. The overall mortality was 3%, whereas the in-hospital mortality after pancreaticoduodenectomy was 5%. The mortality after duodenum-preserving pancreatic head resection was 0%. No statistically significant differences in the hospital stay, blood loss, and serious morbidity were found in either surgery. Operative time was significantly shorter in the duodenum-preserving pancreatic head resection group.

conclusionsBoth pancreatoduodenectomy and duodenum-preserving pancreatic head resection are safe treatment options. Duodenum-preserving pancreatic head resection showed a statistically significant superiority in the operative time compared to pancreaticoduodenectomy. Although other monitored parameters did not show a statistically significant difference, the high risk of complications after pancreaticoduodenectomy with a mortality of 5%; maintenance of the duodenum and upper loop of jejunum, and lower risk of metabolic dysfunctions after duodenum-preserving pancreatic head resection may favour duodenum-preserving pancreatic head resection in recommended diagnoses. Attending physicians should be more encouraged to use a multidisciplinary approach to assess the suitability of surgical treatment in patients with chronic pancreatitis.

Indexed as

Operative TimePancreasPancreaticoduodenectomyPancreatitis, ChronicAdultAgedDuodenumFemaleHospital MortalityHumansLength of StayMaleMiddle AgedOrgan Sparing TreatmentsPancreatectomyPostoperative ComplicationsBegerChronic pancreatitisDuodenum-preserving pancreatic head resectionInflammatory pancreatic head massPancreaticoduodenectomyPancreatic surgery

Identifiers

PMID39358718
PMCPMC11448026

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.