Evidence map›Paper›PMID 39358524›Full record

ArticleNature2024

Predicting visual function by interpreting a neuronal wiring diagram.

H Sebastian Seung

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
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  9. Sexual dimorphism in the complete connectome of thebioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

H Sebastian SeungNeuroscience Institute and Computer Science Department, Princeton University, Princeton, NJ, USA. sseung@princeton.edu.ORCID 0000-0002-8591-6733

Funding

BRAIN CONNECTS: A Center for High-throughput Integrative Mouse ConnectomicsUM1NS132250 · NINDS · HARVARD UNIVERSITY · PI Jeff W Lichtman · 2023 to 2026
$24.9M
Project-003UM1NS132253 · NINDS · ALLEN INSTITUTE · PI Forrest Christie Collman, Nuno Macarico da Costa · 2023 to 2026
$24.8M
P5: Mechanistic Multi-Region Brain ModelsU19NS132720 · NINDS · PRINCETON UNIVERSITY · PI Carlos D Brody, Ila R. Fiete · 2023 to 2026
$21.5M
Structure and Function of a Cubic Millimeter of Cortex: Crowdsourcing for Proofreading and DiscoveryRF1MH123400 · NIMH · PRINCETON UNIVERSITY · PI SEUNG, HYUNJUNE SEBASTIAN · 2020 to 2020
$6.4M
Virtual Observatory of the Cortex: Organelles, Cells, Circuits, and DynamicsU24NS120053 · NINDS · ALLEN INSTITUTE · PI Forrest Christie Collman, Nuno Macarico da Costa · 2022 to 2026
$6.1M
Dissemination of FlyWire, A Whole-Brain Connectomics ResourceU24NS126935 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2022 to 2026
$5.6M
Accelerating connectomic proofreading for larger brains and multiple individualsRF1MH129268 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA · 2022 to 2022
$2.1M
NIMH NIH HHS RF1 MH123400NIMH NIH HHS RF1 MH129268NINDS NIH HHS U19 NS132720NINDS NIH HHS U24 NS120053NINDS NIH HHS U24 NS126935NINDS NIH HHS UM1 NS132250NINDS NIH HHS UM1 NS132253
6 · The paper itself

Abstract

As connectomics advances, it will become commonplace to know far more about the structure of a nervous system than about its function. The starting point for many investigations will become neuronal wiring diagrams, which will be interpreted to make theoretical predictions about function. Here I demonstrate this emerging approach with the Drosophila optic lobe, analysing its structure to predict that three Dm3 (refs.

Indexed as

Drosophila melanogasterModels, AnatomicModels, NeurologicalNeuronsVisual PathwaysVisual PerceptionAnimalsBrainConnectomeFemaleNerve NetNeurophysiologyOptic Lobe, NonmammalianPhotic StimulationSynapses

Identifiers

PMID39358524
PMCPMC11446822

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.