ArticleJournal of exposure science & environmental epidemiology2025
Proteomic biomarkers of long-term lung function decline in textile workers: a 35-year longitudinal study.
Article in Journal of exposure science & environmental epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Proteomic profiling reveals immunologic mediators of endotoxin-related lung function decline: a longitudinal prospective study in textile workers.Respiratory research · 2026Article
- Proteomic Profiling of Pulmonary Function and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study.Journal of the American Heart Association · 2026Observational
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Authors and funding
11 authors.
Funding
Abstract
backgroundOccupational exposures contribute significantly to obstructive lung disease among textile workers. However, biomarkers associated with such declines are not available.
objectivesWe conducted a large-scale proteomic study to explore protein biomarkers potentially associated with long-term lung function decline.
methodsShanghai Textile Workers Cohort was established in 1981 with 35 years of follow-up, assessing textile workers' lung functions every five years. Quantitative serum proteomics was performed on all 453 workers at 2016 survey. We employed four distinct models to examine the association between forced expiratory volume in one second (FEV
results15 of 907 analyzed proteins displayed potential associations with long-term FEV IMPACT STATEMENT: We performed a large-scale proteomic study of the longest-follow-up pulmonary function cohort of textile workers to date. We discovered multiple novel proteins associated with long-term decline of FEV
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