ArticleScientific reports2024
A high-efficiency and selective fluorescent assay for the detection of tetracyclines.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Raspberry-shaped H-COF-based dual-mode fluorescent sensing probe for tetracycline antibiotics: standalone and electrospun mat-based point-of-care applications.Mikrochimica acta · 2026Article
- Highly selective sensing of tetracycline by fluorescent carbon dots derived from spent coffee groundsRSC advances · 2025Article
- A Green-Synthesized Fluorescent Carbon Dot Probe Derived from Banana Peel for Cellular Imaging and Sensing of Tetracycline.Materials (Basel, Switzerland) · 2025Article
- Tetracycline detection via carbon dots-Fe coordination from Chromolaena odorata using a portable device.Analytical and bioanalytical chemistry · 2025Article
- Preparation of Electrochemical Sensors Based on Graphene/Ionic Liquids and the Quantitative Detection and Toxicity Evaluation of Tetracycline.Nanomaterials (Basel, Switzerland) · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Tetracyclines (TCs) rank second globally in the use of animal infection therapy and animal husbandry as growth promoters among all antibiotics. However, large amounts of TCs residue in food products and more than 75% of TCs are excreted into the environment, causing adverse effects on the ecological system and human health. It has been challenging to simultaneously realize low-cost, rapid, and highly selective detection of TCs. Here, inspired by the fluorogenic reactions between resorcinol and catecholamines, we find the fluorescence quenching ability of tetracycline (TC) and firstly propose a fluorescent "turn-off" detection of TC using dopamine and 4-fluororesorcinol. The optimal reaction condition for the fluorescent assay is investigated and the optimized probe showed a good limit of detection (LOD of 1.7 µM) and a wide linear range (10 µM to 350 µM). Moreover, this fluorescent assay proved to be an effective tool for detecting TC in river, Sprite, and beer samples, which represent the aquatic environments and food and may contain tetracyclines residues. Finally, the high selectivity of the method for TC has been confirmed by eliminating the interference from common substances. The proposed strategy provides a high-efficiency and selective solution for the detection of TCs in environment and food and the application fields of this fluorescent assay could be further expanded in the future.
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Registered trials
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