Evidence map›Paper›PMID 39358381›Full record

ArticleScientific reports2024

Psychiatrists effect on positive symptom severity and daily functioning during pharmacotherapy for first-episode psychosis patients.

Franciska de Beer, Sanne Koops, Robert A Schoevers, Wim Veling, Nico van Beveren, Lieuwe de Haan, Nynke Boonstra, Martijn Kikkert, Marieke J H Begemann, HAMLETT-OPHELIA Consortium and 2 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Franciska de BeerDepartment of Biomedical Sciences, University of Groningen, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AW, Groningen, The Netherlands. f.de.beer@umcg.nl.
Sanne KoopsDepartment of Biomedical Sciences, University of Groningen, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AW, Groningen, The Netherlands.
Robert A SchoeversDepartment of Psychiatry, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Wim VelingDepartment of Psychiatry, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Nico van BeverenParnassia Group for Mental Health Care, The Hague, The Netherlands.
Lieuwe de HaanDepartment of Psychiatry, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Nynke BoonstraDepartment of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.
Martijn KikkertArkin, Institute for Mental Health, Amsterdam, The Netherlands.
Marieke J H BegemannDepartment of Biomedical Sciences, University of Groningen, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AW, Groningen, The Netherlands.
HAMLETT-OPHELIA Consortium
Joran LokkerbolCentre of Economic Evaluations and Machine Learning, Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.
Iris E C SommerDepartment of Biomedical Sciences, University of Groningen, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AW, Groningen, The Netherlands.

Funding

ZonMw 348041003
6 · The paper itself

Abstract

Clinical outcomes after a first-episode of psychosis (FEP) are heterogeneous. Many patient-related factors such as gender and comorbidity have been studied to predict symptomatic outcomes. However, psychiatrist-related factors such as prescription behaviour and gender have received little attention. We assessed the relationship between patients' psychiatrists, psychosis severity and daily functioning in 201 patients remitted from an FEP for a duration of one year, treated by 18 different psychiatrists. We controlled for baseline severity, dose and type of antipsychotic medication, frequency of visits, and patients' education. Symptom severity, daily functioning, and antipsychotic drug use were assessed at baseline and at 3, 6, and, 12 months follow-up. We found that psychiatrists accounted for 9.1% of the explained variance in patients' symptom severity and 10.1% of the explained variance in daily functioning.These effects persisted even when controlling for factors such as baseline severity and the prescribed dose. The effect of prescribed dose on symptom severity and daily functioning differed between psychiatrists. Treatment centre, session frequency, and medication nonadherence were not related to symptom severity. Our results emphasize the importance of individual psychiatrist factors in symptomatic outcomes after an FEP. Further identification of psychiatrist-related factors such as the quality of therapeutic alliances and shared decision-making, may optimize psychiatrists' training with the goal of improving patient outcomes.

Indexed as

Antipsychotic AgentsPsychotic DisordersSeverity of Illness IndexActivities of Daily LivingFemaleHumansMalePsychiatristsPsychiatryTreatment OutcomeAntipsychotic AgentsAntipsychotic agentsPsychiatristsPsychotic disordersSeverity of illnessTreatment outcome

Identifiers

PMID39358381
PMCPMC11447264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.