Evidence map›Paper›PMID 39356768›Full record

ArticleScience advances2024

Pachytene piRNAs control discrete meiotic events during spermatogenesis and restrict gene expression in space and time.

Jacob Ortega, Lamia Wahba, Jacob Seemann, Shin-Yu Chen, Andrew Z Fire, Swathi Arur

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. piRNAs safeguard splicing and RNA fidelity during heat shock.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jacob OrtegaProgram in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-9294-8477
Lamia WahbaDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-8369-6864
Jacob SeemannDepartment of Genetics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-5113-9788
Shin-Yu ChenDepartment of Genetics, UT MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-8174-7741
Andrew Z FireDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-6217-8312
Swathi ArurProgram in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-6941-2711

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Cellular Response to Genetic ChangeR35GM130366 · NIGMS · STANFORD UNIVERSITY · PI ANDREW Z. FIRE · 2019 to 2026
$4.8M
Erk-mediated regulation of Dicer and Drosha function in C. elegansR01GM098200 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ARUR, SWATHI · 2011 to 2020
$3.3M
How Post-Translational Codes and Small RNA Pathways Shape Developmental OutcomesR35GM140933 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Swathi Arur · 2021 to 2026
$2.5M
NIGMS NIH HHS R01 GM098200NIGMS NIH HHS R35 GM130366NIGMS NIH HHS R35 GM140933NIH HHS P40 OD010440
6 · The paper itself

Abstract

Pachytene piRNAs, a Piwi-interacting RNA subclass in mammals, are hypothesized to regulate non-transposon sequences during spermatogenesis.

Indexed as

Caenorhabditis elegansMeiosisPachytene StageRNA, Small InterferingSpermatogenesisAnimalsCaenorhabditis elegans ProteinsGene Expression RegulationMalePiwi-Interacting RNAProtein Serine-Threonine KinasesCaenorhabditis elegans ProteinsPiwi-Interacting RNAProtein Serine-Threonine KinasesRNA, Small Interfering

Identifiers

PMID39356768
PMCPMC11446278

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.