ArticleIEEE transactions on bio-medical engineering2025
Four-Dimensional (4D) Ultrasound Shear Wave Elastography Using Sequential Excitation.
Article in IEEE transactions on bio-medical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Four-Dimensional Sequential Elastography for Ocular Tissue Using 2D Matrix Array.BME frontiers · 2026Article
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9 authors.
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Abstract
objectiveCurrent shear wave elastography methods primarily focus on 2D imaging. To explore mechanical properties of biological tissues in 3D, a four-dimensional (4D, x, y, z, t) ultrasound shear wave elastography is required. However, 4D ultrasound shear wave elastography is still challenging due to the limitation of the hardware of standard ultrasound acquisition systems. In this study, we introduce a novel method to achieve 4D shear wave elastography, named sequential-based excitation shear wave elastography (SE-SWE). This method can achieve 4D elastography implemented by a 1024-element 2D array with a standard ultrasound 256-channel system.
methodsThe SE-SWE method employs sequential excitation to generate shear waves, and utilizes a 2D array, dividing it into four sub-sections, to capture shear waves across multiple planes. This process involves sequentially exciting each sub-section to capture shear waves, followed by compounding the acquired data from these subsections.
resultsThe phantom studies showed strong concordance between the shear wave speeds (SWS) measured by SE-SWE and expected values, confirming the accuracy of this method and potential to differentiate tissues by stiffness. In ex vivo chicken breast experiments, SE-SWE effectively distinguished between orientations relative to muscle fibers, highlighting its ability to capture the anisotropic properties of tissues.
conclusionThe SE-SWE method advances shear wave elastography significantly by using a 2D array divided into four subsections and sequential excitation, achieving high-resolution volumetric imaging at 1.6mm resolution. SIGNIFICANCE: The SE-SWE method offers a straightforward and effective approach for 3D shear volume imaging of tissue biological properties.
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