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ArticleJapanese journal of ophthalmology2024

Associations of ocular anterior segment structures with sex and age: the Yamagata study (Funagata).

Hiroyuki Namba, Naoyuki Maeda, Makoto Tsukamoto, Hiroshi Utsunomiya, Yutaka Kaneko, Koichi Nishitsuka, Hidetoshi Yamashita, Yasuyuki Ohta, Tomohiko Usui, Masahiko Sugimoto

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In one paragraph

Article in Japanese journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Longitudinal change in anterior chamber depth and its determinants: a median 4.9-year follow-up of 2,247 Japanese adults.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroyuki NambaDepartment of Ophthalmology, International University of Health and Welfare School of Medicine, 852 Hatakeda, Narita City, 286-0124, Chiba Prefecture, Japan. hnamba@iuhw.ac.jp.ORCID http://orcid.org/0000-0002-3879-7970
Naoyuki MaedaDepartment of Ophthalmology, Osaka University Graduate School of Medicine, Suita City, Osaka, Japan.
Makoto TsukamotoTomey Corporation, Nagoya City, Aichi, Japan.
Hiroshi UtsunomiyaDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Yutaka KanekoDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Koichi NishitsukaDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Hidetoshi YamashitaDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Yasuyuki OhtaDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Tomohiko UsuiDepartment of Ophthalmology, International University of Health and Welfare School of Medicine, 852 Hatakeda, Narita City, 286-0124, Chiba Prefecture, Japan.
Masahiko SugimotoDepartment of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.

Funding

Tomey Corporation Tomey Corporation
6 · The paper itself

Abstract

purposeTo investigate the associations of tomographic parameters in anterior segment optical coherence tomography (AS-OCT) with sex and age in a cohort study. STUDY

designA cohort design. MATERIALS AND

methodsAS-OCT data from 391 Japanese participants aged ≥ 35 years were obtained using swept-source OCT. In the cornea, the keratometric power at the flat (Kf) and steep (Ks) meridians, maximum keratometric power (Kmax), keratometric cylinder, spherical power, regular astigmatism, asymmetry, higher-order irregularity (HOI) from the anterior and posterior surfaces, and the central and thinnest corneal thicknesses were evaluated. Also, anterior chamber depth (ACD), lens thickness, crystalline lens rise (CLR), and nasal and temporal angle opening distances at 500 μm from the scleral spur (AOD500) were assessed. Sex differences and age-related changes were analyzed.

resultsWomen exhibited higher anterior Kf, Ks, and Kmax and lower posterior Kf, Ks, and Kmax than men. The ACD and nasal/temporal AOD500 were shorter in women than in men. The CLR was higher in women, whereas the lens thickness did not differ between the sexes, indicating a more anteriorly positioned lens in women. Age-related changes included increased anterior/posterior HOI, increased lens thickness and CLR resulting in decreased ACD and AOD500.

conclusionThis study reveals sex-related differences in corneal shape, anterior chamber conformation, and lens position, as well as age-related changes in tomographic parameters. ACD, CLR, nasal and temporal AOD500 showed significant sex differences in the 50-70 s, whereas lens thickness showed no difference.

Indexed as

Anterior Eye SegmentTomography, Optical CoherenceAdultAgedAged, 80 and overAge FactorsAgingCorneaFemaleHumansJapanMaleMiddle AgedSex FactorsAnterior segmentCorneaKeratometryOptical coherence tomographySex difference

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.