Evidence map›Paper›PMID 39356076›Full record

ArticleJournal of neurophysiology2024

Role of the Kölliker-Fuse/parabrachial complex in the generation of postinspiratory vagal and sympathetic nerve activities and their recruitment by hypoxemic stimuli in the rat.

Rahat Ul Ain Summan Toor, Peter G R Burke, Bowen Dempsey, Qi-Jian Sun, Cara M Hildreth, Jacqueline K Phillips, Simon McMullan

Abstract read
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In one paragraph

Article in Journal of neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Role of the KF/PBN in postinspiration.Journal of neurophysiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rahat Ul Ain Summan ToorMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.
Peter G R BurkeMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.ORCID 0000-0002-6896-3298
Bowen DempseyMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.
Qi-Jian SunMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.
Cara M HildrethMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.
Jacqueline K PhillipsMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.ORCID 0000-0002-4917-7734
Simon McMullanMacquarie Medical School, Faculty of Medicine, Health and Human SciencesMacquarie University, Sydney, Australia.ORCID 0000-0002-9854-1029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the rat, the activity of laryngeal adductor muscles, the crural diaphragm, and sympathetic vasomotor neurons is entrained to the postinspiratory (post-I) phase of the respiratory cycle, a mechanism thought to enhance cardiorespiratory efficiency. The identity of the central neurons responsible for transmitting respiratory activity to these outputs remains unresolved. Here we explore the contribution of the Kölliker-Fuse/parabrachial nuclei (KF-PBN) in the generation of post-I activity in vagal and sympathetic outputs under steady-state conditions and during acute hypoxemia, a condition that potently recruits post-I activity. In artificially ventilated, vagotomized, and urethane-anesthetized rats, bilateral KF-PBN inhibition by microinjection of the GABA

Indexed as

HypoxiaKolliker-Fuse NucleusSympathetic Nervous SystemVagus NerveAnimalsGABA-A Receptor AgonistsIsonicotinic AcidsMaleParabrachial NucleusPhrenic NerveRatsRats, Sprague-DawleyRespirationGABA-A Receptor AgonistsisoguvacineIsonicotinic Acidschemoreflexhypoxiarespiratory-sympathetic coupling

Identifiers

PMID39356076

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.