Evidence map›Paper›PMID 39355804›Full record

ReviewJournal of orthopaedics2025

Meta-analysis of 65 Adamantinoma case reports: Unveiling symptomatology, demographics, and treatment outcomes in contrast to prior understandings.

Vijay Patel, Santiago Ortiz, Alessandra Ottley, Aidan Kaspari, Patrick Laird, Gary Schwartz

Abstract readReview
In one paragraph

Review in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vijay PatelKiran C. Patel College of Osteopathic Medicine, USA.
Santiago OrtizKiran C. Patel College of Osteopathic Medicine, USA.
Alessandra OttleyKiran C. Patel College of Osteopathic Medicine, USA.
Aidan KaspariKiran C. Patel College of Osteopathic Medicine, USA.
Patrick LairdBroward Health Department of Orthopedics, USA.
Gary SchwartzKiran C. Patel College of Allopathic Medicine, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adamantinomas are rare, malignant bone tumors predominantly affecting the tibia. This study compares demographics, clinical presentations, radiographic findings, metastasis rates, and treatment outcomes of adamantinoma cases from a contemporary review of 65 cases with a historical review by Keeney et al. (1989). Our data reveals a significant increase in the average age at diagnosis, from 25.9 years in the prior study to 38.1 years in the new study, with notable increases for both males and females. The metastasis rate in our study was 45.3 %, significantly higher than the 23.5 % reported previously with a wider range of possible sites. Treatment options have changed with significant improvement in survivability and remission with allograft and endoprosthesis techniques compared to older techniques of amputation and resection. This study highlights the evolving understanding of adamantinoma, emphasizing the changes in presentation and the effectiveness of advanced surgical treatments.

Identifiers

PMID39355804
PMCPMC11440282

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.