Evidence map›Paper›PMID 39355758›Full record

ArticleIn silico pharmacology2024

Computational targeting of iron uptake proteins in Covid-19 induced mucormycosis to identify inhibitors via molecular dynamics, molecular mechanics and density function theory studies.

Manjima Sen, B M Priyanka, D Anusha, S Puneetha, Anagha S Setlur, Chandrashekar Karunakaran, Amulya Tandur, C S Prashant, Vidya Niranjan

Abstract read
In one paragraph

Article in In silico pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manjima SenDepartment of Public Health Dentistry, DAPM RV Dental College, Bangalore, 560078 India.
B M PriyankaDepartment of Oral Medicine and Diagnostic Radiology, DAPM RV Dental College, Bangalore, 560078 India.
D AnushaDepartment of Periodontia, DAPM RV Dental College, Bangalore, 560078 India.
S PuneethaDepartment of Oral Pathology and Microbiology, DAPM RV Dental College, Bangalore, 560078 India.
Anagha S SetlurDepartment of Biotechnology, RV College of Engineering, Bangalore, 560059 India.
Chandrashekar KarunakaranDepartment of Biotechnology, RV College of Engineering, Bangalore, 560059 India.
Amulya TandurDepartment of Biotechnology, RV College of Engineering, Bangalore, 560059 India.
C S PrashantDepartment of Orthodontics, DAPM RV Dental College, Bangalore, 560078 India.
Vidya NiranjanDepartment of Biotechnology, RV College of Engineering, Bangalore, 560059 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is a concerning invasive fungal infection with difficult diagnosis, high mortality rates, and limited treatment options. Iron availability is crucial for fungal growth that causes this disease. This study aimed to computationally target iron uptake proteins in Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-024-00264-7.

Indexed as

Density function theoryIron uptake proteinsMM-GBSAMolecular docking and simulationsMucormycosisQuantum mechanics

Identifiers

PMID39355758
PMCPMC11439861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.