Evidence map›Paper›PMID 39355498›Full record

ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2024

Management of severe acute respiratory distress syndrome in Australia and New Zealand (SAGE-ANZ): An observational study.

Rachael L Parke, Shay P McGuinness, Alana Cavadino, Keri-Anne Cowdrey, Samantha Bates, Shailesh Bihari, Amanda Corley, Eileen Gilder, Carol Hodgson, Edward Litton and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ARDS, guidelines and ANZ practice: The persistent disconnect.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rachael L ParkeCardiothoracic and Vascular Intensive Care Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
Shay P McGuinnessCardiothoracic and Vascular Intensive Care Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
Alana CavadinoSchool of Population Health, The University of Auckland, Auckland, New Zealand.
Keri-Anne CowdreyCardiothoracic and Vascular Intensive Care Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
Samantha BatesDepartment of Intensive Care, Western Health, VIC, Australia.
Shailesh BihariCollege of Medicine and Public Health, Flinders University, Bedford Park, South Australia 5042, Australia.
Amanda CorleyCritical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.
Eileen GilderCardiothoracic and Vascular Intensive Care Unit, Te Toka Tumai Auckland, Auckland, New Zealand.
Carol HodgsonAustralian and New Zealand Intensive Care Centre, Monash University, Melbourne, Australia.
Edward LittonIntensive Care Unit, Fiona Stanley Hospital, Perth Australia.
Colin McArthurMedical Research Institute of New Zealand, Wellington, New Zealand.
Alistair NicholAustralian and New Zealand Intensive Care Centre, Monash University, Melbourne, Australia.
Jane ParkerAustralian and New Zealand Intensive Care Centre, Monash University, Melbourne, Australia.
Anne TurnerMedical Research Institute of New Zealand, Wellington, New Zealand.
Steve WebbAustralian and New Zealand Intensive Care Centre, Monash University, Melbourne, Australia.
Frank Mp Van HarenIntensive Care Unit, St George Hospital, Sydney, Australia.
SAGE-ANZ Study Investigators and the Australia and New Zealand Intensive Care Society Clinical Trials Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Acute respiratory distress syndrome (ARDS) is associated with significant mortality, morbidity, and cost. We aimed to describe characteristics and management of adult patients admitted to intensive care units (ICUs) in Australia and New Zealand with moderate-severe ARDS, to better understand contemporary practice. Design: Bi-national, prospective, observational, multi-centre study. Setting: 19 ICUs in Australia and New Zealand. Participants: Mechanically ventilated patients with moderate-severe ARDS. Main outcome measures: Baseline demographic characteristics, ventilation characteristics, use of adjunctive support therapy and all-cause mortality to day 28. Data were summarised using descriptive statistics. Results: 200 participants were enrolled, mean (±SD) age 55.5 (±15.9) years, 40% (n = 80) female. Around half (51.5%) had no baseline comorbidities and 45 (31%) tested positive for COVID-19. On day 1, mean SOFA score was 9 ± 3; median (IQR) PaO Conclusions: In Australia and New Zealand, compliance with evidence-based practices including LPV and prone positioning was low in this cohort. Therapies with proven benefit in the treatment of patients with moderate-severe ARDS, such as lung protective ventilation and prone positioning, were not routinely employed.

Indexed as

Acute respiratory distress syndrome: adjunctive therapyLung protective ventilationMechanical ventilationProne positioning

Identifiers

PMID39355498
PMCPMC11440055

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.