ReviewCureus2024
Pulmonary Embolism and Right Ventricular Dysfunction: Mechanism and Management.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Prognostic performance of the oxygenation-modified shock index in predicting in-hospital mortality in acute pulmonary embolism.Irish journal of medical science · 2026Article
- Long non-coding RNA SNHG6 promotes the proliferation of PASMCs cells through the miR-429/DUSP1 axis during early/subacute vascular responses to pulmonary embolism.Molecular and cellular biochemistry · 2026Article
- Development of the THROMPE score for predicting centrally located pulmonary embolism: a retrospective cohort study.Internal and emergency medicine · 2026Article
- Inpatient Outcomes of Pulmonary Embolism in Patients with Inflammatory Bowel Disease: Insights from a Nationwide Analysis.Journal of clinical medicine · 2026Article
- The Right Ventricle in Cardiac Critical Care: Pathophysiology, Evaluation and Management.Medicina (Kaunas, Lithuania) · 2026Review
- A Narrative Review of Right Heart Dysfunction in Pulmonary Embolism: Current Insights and Clinical Perspectives.Cureus · 2026Review
- Reperfusion Pulmonary Hemorrhage Following Mechanical Thrombectomy for Sub-massive Pulmonary Embolism.Cureus · 2026Article
- Pulmonary embolism consensus.Archivos de cardiologia de Mexico · 2026Article
- Knowledge, attitude, and practice of orthopedic surgery patients regarding the prevention and treatment of venous thromboembolism.Frontiers in public health · 2026Article
- Identification, Evaluation, and Management of Perioperative Right Ventricular Dysfunction in Noncardiac Surgery: A Multimodal Approach.Journal of cardiothoracic and vascular anesthesia · 2025Review
- Syncope and In-Hospital Mortality in Pulmonary Embolism: Insights from 300 Patients.Life (Basel, Switzerland) · 2025Article
- Association of controlling nutritional status score and long-term mortality in acute pulmonary embolism.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025Article
- Beyond a Single Marker: An Update on the Comprehensive Evaluation of Right Ventricular Dysfunction in Pulmonary Thromboembolism.Life (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary embolism (PE) occurs when thrombi from deep vein thrombosis dislodge and obstruct pulmonary arteries, raising pulmonary artery pressure and straining the right ventricle. This strain can lead to right ventricular dysfunction (RVD), characterized by reduced cardiac output, impaired contractility, and potential development of chronic thromboembolic pulmonary hypertension. Clinically, PE may present with symptoms such as dyspnea, pleuritic chest pain, and tachycardia. Diagnosis is typically confirmed through computed tomography pulmonary angiography, biomarkers like D-dimer and cardiac troponins, and clinical scoring systems. Acute management focuses on hemodynamic support, including intravenous fluids and vasopressors, and may involve anticoagulation with low-molecular-weight heparin or direct oral anticoagulants. Severe cases may require systemic anticoagulation, catheter-directed techniques, and surgeries like pulmonary endarterectomy. Long-term management involves continued anticoagulation tailored to individual risk factors, with ongoing monitoring to prevent recurrence. Effective early diagnosis and management are crucial, as severe PE can significantly increase mortality and lead to serious complications. This review explores the pathophysiology, diagnosis, and management of PE and RVD.
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Registered trials
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