Evidence map›Paper›PMID 39355086›Full record

ReviewAdvanced functional materials2024

Strategies for Making High-Performance Artificial Spider Silk Fibers.

Benjamin Schmuck, Gabriele Greco, Tomas Bohn Pessatti, Sumalata Sonavane, Viktoria Langwallner, Tina Arndt, Anna Rising

Abstract readReview
In one paragraph

Review in Advanced functional materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Ecosystem services provided by spiders.Biological reviews of the Cambridge Philosophical Society · 2025
    Review
  7. Nanostructured Protein Surfaces Inspired by Spider Silk.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  8. Review
  9. Article
  10. Manipulating the Assembly and Architecture of Fibrillar Silk.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Exploring the functional properties ofMaterials today. Communications · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin SchmuckDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0000-0003-4021-6458
Gabriele GrecoDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0000-0003-3356-7081
Tomas Bohn PessattiDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0000-0003-4497-3157
Sumalata SonavaneDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0000-0002-0728-4822
Viktoria LangwallnerDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0009-0006-8815-534X
Tina ArndtDepartment of Biosciences and Nutrition Karolinska Institutet, Neo Huddinge 14186 Sweden.ORCID https://orcid.org/0000-0002-5190-0039
Anna RisingDepartment of Anatomy, Physiology, and Biochemistry Swedish University of Agricultural Sciences Box 7011 Uppsala 75007 Sweden.ORCID https://orcid.org/0000-0002-1872-1207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial spider silk is an attractive material for many technical applications since it is a biobased fiber that can be produced under ambient conditions but still outcompetes synthetic fibers (e.g., Kevlar) in terms of toughness. Industrial use of this material requires bulk-scale production of recombinant spider silk proteins in heterologous host and replication of the pristine fiber's mechanical properties. High molecular weight spider silk proteins can be spun into fibers with impressive mechanical properties, but the production levels are too low to allow commercialization of the material. Small spider silk proteins, on the other hand, can be produced at yields that are compatible with industrial use, but the mechanical properties of such fibers need to be improved. Here, the literature on wet-spinning of artificial spider silk fibers is summarized and analyzed with a focus on mechanical performance. Furthermore, several strategies for how to improve the properties of such fibers, including optimized protein composition, smarter spinning setups, innovative protein engineering, chemical and physical crosslinking as well as the incorporation of nanomaterials in composite fibers, are outlined and discussed.

Indexed as

biomimetic spinningmechanical propertiesprotein fibersrational designswet‐spinning

Identifiers

PMID39355086
PMCPMC11440630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.