Evidence map›Paper›PMID 39355023›Full record

ArticleFrontiers in nuclear medicine2023

Case report: Efficacy of lutetium-177 oxodotreotide for neuroendocrine tumor with central nervous system metastases.

Nwanneka Okwundu, Christopher R Weil, Heloisa P Soares, Gabriel C Fine, Donald M Cannon

Abstract readCase Reports
In one paragraph

Article in Frontiers in nuclear medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nwanneka OkwunduDepartment of Radiation Oncology, University of Utah School of Medicine, Salt Lake City, UT, United States.
Christopher R WeilDepartment of Radiation Oncology, University of Utah School of Medicine, Salt Lake City, UT, United States.
Heloisa P SoaresDepartment of Medical Oncology, University of Utah School of Medicine, Salt Lake City, UT, United States.
Gabriel C FineDepartment of Nuclear Medicine, University of Utah, Salt Lake City, UT, United States.
Donald M CannonDepartment of Radiation Oncology, University of Utah School of Medicine, Salt Lake City, UT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) rarely metastasize to the brain. However, when they occur, NET brain metastases are associated with a poor prognosis. Due to their low incidence, NET brain metastases are poorly studied, with few data to guide a consensus for management. Prior reports have documented treatment with chemotherapy, resection, whole brain radiation therapy, and stereotactic radiosurgery, all with low rates of survival. We present a case of a patient with type 3 well-differentiated gastric NET with widespread metastatic disease, including central nervous system lesions in the pineal gland and left cerebellopontine angle (CPA), which were avid on

Indexed as

central nervous systemlutetium (177Lu)-DOTA-octreotat (DOTATATE)metastasesneuroendocrine tumorpeptide receptor radionuclide therapy (PRRT)

Identifiers

PMID39355023
PMCPMC11440844

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.