Evidence map›Paper›PMID 39354580›Full record

ArticleNeurological research and practice2024

Association of intraprocedural near admission-level blood pressure with functional outcome in stroke patients treated with mechanical thrombectomy.

Min Chen, Lukas Daniel Sauer, Mika Herwig, Jessica Jesser, Meinhard Kieser, Arne Potreck, Markus Möhlenbruch, Peter Arthur Ringleb, Silvia Schönenberger

Abstract read
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Article in Neurological research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Min ChenDepartment of Neurology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany. min.chen@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0001-9079-9298
Lukas Daniel SauerInstitute of Medical Biometry, Heidelberg University, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.
Mika HerwigDepartment of Neurology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Jessica JesserDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Meinhard KieserInstitute of Medical Biometry, Heidelberg University, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany.
Arne PotreckDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Markus MöhlenbruchDepartment of Neuroradiology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Peter Arthur RinglebDepartment of Neurology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.
Silvia SchönenbergerDepartment of Neurology, Heidelberg University Hospital, Heidelberg University, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOptimal blood pressure management during endovascular stroke treatment is not certain. We hypothesized that time or proportion of intraprocedural systolic blood pressure spent in a range around admission blood pressure might be associated with better clinical outcome.

methodsWe conducted a retrospective observational study at a single center at a university hospital, which included patients from August 2018 to September 2020 suffering from acute ischemic stroke with anterior circulation vessel occlusion and treated with endovascular therapy. Time and proportion of procedure time where systolic blood pressure (SBP) was near the baseline SBP on admission (bSBP) were used as exposure variables. The primary outcome was the occurrence of mRS score 0-2 three months after stroke. The primary analysis was performed by fitting a logistic regression model adjusted for baseline NIHSS, pre-stroke mRS, mTICI score, intubation, age and sex.

resultsWe included 589 patients in the analysis. Mean (SD) age was 76 (12) years, 315 were women (53%) and mean (SD) NIHSS score at admission was 15 (7.5). Mean (SD) bSBP was 167 (28) mmHg and mean (SD) intraprocedural SBP was 147 (21) mmHg. The proportion of time where intraprocedural SBP was in range of bSBP ± 20% was associated with a slightly higher odds of achieving favorable outcome (adjusted OR, 1.007; 95% CI, 1.0003-1.013).

conclusionA higher proportion of intraprocedural time with systolic blood pressure in range of ± 20% of the admission level is associated with higher odds of favorable functional outcome.

trial registrationNot applicable.

Indexed as

Blood pressureEndovascular stroke treatmentPeriprocedural management

Identifiers

PMID39354580
PMCPMC11443703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.