Evidence map›Paper›PMID 39354476›Full record

ArticleJournal of nanobiotechnology2024

NIR-activatable nitric oxide generator based on nanoparticles loaded small-molecule photosensitizers for synergetic photodynamic/gas therapy.

Lili Fu, Yan Huang, Xin Shan, Xiao Sun, Xinlei Wang, Xiaoyan Wang, Lingxin Chen, Shui Yu

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lili FuSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China.
Yan HuangSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China. yhuang@yic.ac.cn.
Xin ShanDepartment of Intelligent Manufacturing, Shandong City Service Institute, Yantai, 264003, China.
Xiao SunSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China.
Xinlei WangSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China.
Xiaoyan WangSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China.
Lingxin ChenSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China. lxchen@yic.ac.cn.
Shui YuSchool of Pharmacy, Binzhou Medical University, Yantai, 264003, China. yushui_0121@163.com.

Funding

National Natural Science Foundation of China 21804010National Natural Science Foundation of China 22007005Research Initiation Fund of Binzhou Medical University 50012304601Research Initiation Fund of Binzhou Medical University BY2019KYQD39Research Initiation Fund of Binzhou Medical University BY2020KYQD01Shandong Peninsula Engineering Research Center of Comprehensive Brine Utilization 2018LS014Taishan Scholar Project Special Funding ts20190962
6 · The paper itself

Abstract

backgroundTherapeutic approaches that combine conventional photodynamic therapy (PDT) with gas therapy (GT) to sensitize PDT are an attractive strategy, but the molecular structure design of the complex lacks effective guiding strategies.

resultsHerein, we have developed a nanoplatforms Cy-NMNO@SiO

conclusionsThis work not only offers a promising approach for PDT-GT synergistic drug delivery system, but also provides a valuable reference for the design of its drug molecules.

Indexed as

NanoparticlesNitric OxidePhotochemotherapyPhotosensitizing AgentsSilicon DioxideAnimalsAnti-Bacterial AgentsCell Line, TumorCell SurvivalDrug Delivery SystemsHumansInfrared RaysMiceMice, Inbred BALB CSkin NeoplasmsAnti-Bacterial AgentsNitric OxidePhotosensitizing AgentsSilicon DioxideMesoporous silica materialsNanoplatformsNitric oxide releasePhotodynamic therapySmall-molecule photosensitizers

Identifiers

PMID39354476
PMCPMC11446090

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.