ArticleScientific reports2024
New ultrasound features in diagnosing fetal anal atresia: a multicenter prospective cohort study.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cost-effectiveness analysis of AI-based image quality control for perinatal ultrasound screening.BMC medical education · 2024Trial
- Fetal intestinal dilatation and digestive tract abnormalities: an analysis of 94 cases from 16,090 deliveries in eastern Tianjin.Frontiers in pediatrics · 2026Article
- Retrospective Evaluation of Transvaginal Sonography, Saline Infusion Sonography, and Hysterosalpingography for Detecting Endometrial Polyps in 256 Infertile Women.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Diagnostic value of prenatal ultrasound in the typing of fetal esophageal atresia.Frontiers in medicine · 2025Article
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Authors and funding
8 authors.
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Abstract
This research aimed to assess the validity of ultrasound scans with new features in detecting fetal anal atresia and verify the effectiveness of these new features. Additionally, we aimed at investigating the perinatal incidence of anal atresia. This multicenter prospective study recruited 94,617 normal gravidas and 84 gravidas with anal atresia fetuses. The gold standard for diagnosing perinatal anal atresia is routine neonatal anus examinations. The incidence calculation was based on the results of the gold standard. The validity of our new approach was evaluated via a diagnostic test involving all 94,701 subjects. The effectiveness of our new features was assessed through an ablation study in a randomly established new dataset, with the ratio of anal atresia to non-anal atresia cases of 1:4. The annual perinatal incidence of anal atresia between 2019 and 2023 ranges from 0.57‰ to 1.29‰. Our new method performed great regarding the Youden index, diagnostic odds ratio (DOR), area under the curve (AUC) of the receiver operating characteristic curve (ROCC), AUC of the precision-recall curve (PRC), F1-score, and Cramer's V. In the ablation study, our new approach surpassed its competitors concerning Youden index, DOR, AUC of the ROCC, and AUC of the PRC. Ultrasound scans show high validity and clinical value in detecting fetal anal atresia. Our new ultrasound features significantly promote the detection of fetal anal atresia.
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