ArticleNature communications2024
Revisiting the activity of two poly(vinyl chloride)- and polyethylene-degrading enzymes.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Exploring the role of oxidative defects in polyethylene binding and degradation by a Rhodococcus opacus R7 multicopper oxidase: a computational perspective.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026Article
- Review
- Biodegradation of components from an oxidized polyethylene by aApplied and environmental microbiology · 2026Article
- Challenges and opportunities in the enzymatic recycling of nylons.Nature chemical biology · 2026Review
- Recent advances in biomass deconstruction, microbial conversion, artificial intelligence, and carbon capture for sustainable bioenergy.Bioresources and bioprocessing · 2026Review
- Review
- Production and Evaluation of Fluorophore-Doped Polymer Substrates to Screen for Plastic-Degrading Enzymes.ACS sustainable chemistry & engineering · 2026Article
- Reflections on bio-based PET and plastic waste management: a responsible research and innovation approach.Nature communications · 2026Review
- Advances in polyethylene biodegradation and bioconversion: Microbial, enzymatic, and biotechnological insights.Engineering microbiology · 2026Review
- Whole-genome assembly and annotation of the bumblebee wax moth, Aphomia sociella.G3 (Bethesda, Md.) · 2026Article
- Harnessing Colloidal Dispersion for Laccase-Driven Enzymatic Depolymerization of Polystyrene.Angewandte Chemie (International ed. in English) · 2026Article
- Microbial plastic degradation: enzymes, pathways, challenges, and perspectives.Microbiology and molecular biology reviews : MMBR · 2025Review
- Plastic Type and Condition Have Minimal Impact on Associated Marine Biofilm Communities.Environmental microbiology · 2025Article
- Insights into Microbial Enzymatic Biodegradation of Plastics and Microplastics: Technological Updates.ACS environmental Au · 2025Review
- Refining Biodegradability Assessments of Polymers Through Microbial Biomolecule Quantification.Polymers · 2025Article
- Addendum: Polyvinyl chloride degradation by a bacterium isolated from the gut of insect larvae.Nature communications · 2025Article
- Degradation of polyvinyl chloride (PVC) microplastics employing the actinobacterial strain Streptomyces gobitricini.Biodegradation · 2025Article
- Review
- Microbial degradation of a widely used model polyethylene is restricted to medium- and long-chain alkanes and their oxidized derivatives.The ISME journal · 2025Article
- Insect farming: A bioeconomy-based opportunity to revalorize plastic wastes.Environmental science and ecotechnology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Biocatalytic degradation of non-hydrolyzable plastics is a rapidly growing field of research, driven by the global accumulation of waste. Enzymes capable of cleaving the carbon-carbon bonds in synthetic polymers are highly sought-after as they may provide tools for environmentally friendly plastic recycling. Despite some reports of oxidative enzymes acting on non-hydrolyzable plastics, including polyethylene or poly(vinyl chloride), the notion that these materials are susceptible to efficient enzymatic degradation remains controversial, partly driven by a general lack of studies independently reproducing previous observations. Here, we attempt to replicate two recent studies reporting that deconstruction of polyethylene and poly(vinyl chloride) can be achieved using an insect hexamerin from Galleria mellonella (so-called "Ceres") or a bacterial catalase-peroxidase from Klebsiella sp., respectively. Reproducing previously described experiments, we do not observe any activity on plastics using multiple reaction conditions and multiple substrate types. Digging deeper into the discrepancies between the previous data and our observations, we show how and why the original experimental results may have been misinterpreted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.