Evidence map›Paper›PMID 39353883›Full record

ArticleCell death & disease2024

Novel FABP4

Dong Zhang, Min Wang, Gen Liu, Xin Li, Wenwen Yu, Zhenzhen Hui, Xiubao Ren, Qian Sun

Abstract read
In one paragraph

Article in Cell death & disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  5. Article
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  8. Senescent SPP1Molecular cancer · 2025
    Article
  9. Article
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong Zhang *Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Min Wang *Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Gen LiuTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Xin LiTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Wenwen YuTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Zhenzhen HuiTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Xiubao RenTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. renxiubao@tjmuch.com.ORCID 0000-0003-4137-2049
Qian SunTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China. sunqian923@126.com.ORCID 0000-0002-4878-3599

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82373283, 82372779, U20A20375
6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) immunotherapy facilitates new approaches to achieve precision cancer treatment. A growing number of patients with non-small cell lung cancer (NSCLC) have benefited from treatment with neoadjuvant ICIs combined with chemotherapy. However, the mechanisms and associations between the therapeutic efficacy of neoadjuvant pembrolizumab and chemotherapy (NAPC) and macrophage subsets are still unclear. We performed single-cell RNA sequencing (scRNA-seq) and identified a novel FABP4

Indexed as

Antibodies, Monoclonal, HumanizedCarcinoma, Non-Small-Cell LungFatty Acid-Binding ProteinsLung NeoplasmsMacrophagesNeoadjuvant TherapyAMP-Activated Protein KinasesAnimalsFemaleHumansJanus KinasesMaleMiceMiddle AgedSignal TransductionSTAT Transcription FactorsAMP-Activated Protein KinasesAntibodies, Monoclonal, HumanizedFABP4 protein, humanFatty Acid-Binding ProteinsJanus KinasespembrolizumabSTAT Transcription Factors

Identifiers

PMID39353883
PMCPMC11445384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.