Evidence map›Paper›PMID 39353705›Full record

ArticleOpen heart2024

Use of artificial intelligence-powered ECG to differentiate between cardiac and pulmonary pathologies in patients with acute dyspnoea in the emergency department.

Ji-Hun Jang, Sang-Won Lee, Dae-Young Kim, Sung-Hee Shin, Sang-Chul Lee, Dae-Hyeok Kim, Wonik Choi, Yong-Soo Baek

Abstract read
In one paragraph

Article in Open heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ji-Hun Jang *Division of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea.
Sang-Won Lee *Department of Electrical and Computer Engineering, Inha University, Incheon, South Korea.
Dae-Young KimDivision of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea.
Sung-Hee ShinDivision of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea.
Sang-Chul LeeDeepCardio Inc, Incheon, South Korea.
Dae-Hyeok KimDivision of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea.
Wonik ChoiDeepCardio Inc, Incheon, South Korea.
Yong-Soo BaekDivision of Cardiology, Department of Internal Medicine, Inha University College of Medicine, Incheon, South Korea existsoo@inha.ac.kr.ORCID 0000-0002-6086-0446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute dyspnoea is common in acute care settings. However, identifying the origin of dyspnoea in the emergency department (ED) is often challenging. We aimed to investigate whether our artificial intelligence (AI)-powered ECG analysis reliably distinguishes between the causes of dyspnoea and evaluate its potential as a clinical triage tool for comparing conventional heart failure diagnostic processes using natriuretic peptides.

methodsA retrospective analysis was conducted using an AI-based ECG algorithm on patients ≥18 years old presenting with dyspnoea at the ED from February 2006 to September 2023. Patients were categorised into cardiac or pulmonary origin groups based on initial admission. The performance of an AI-ECG using a transformer neural network algorithm was assessed to analyse standard 12-lead ECGs for accuracy, sensitivity, specificity and area under the receiver operating characteristic curve (AUC). Additionally, we compared the diagnostic efficacy of AI-ECG models with N-terminal probrain natriuretic peptide (NT-proBNP) levels to identify cardiac origins.

resultsAmong the 3105 patients included in the study, 1197 had cardiac-origin dyspnoea. The AI-ECG model demonstrated an AUC of 0.938 and 88.1% accuracy for cardiac-origin dyspnoea. The sensitivity, specificity and positive and negative predictive values were 93.0%, 79.5%, 89.0% and 86.4%, respectively. The F1 score was 0.828. AI-ECG demonstrated superior diagnostic performance in identifying cardiac-origin dyspnoea compared with NT-proBNP. True cardiac origin was confirmed in 96 patients in a sensitivity analysis of 129 patients with a high probability of cardiac origin initially misdiagnosed as pulmonary origin predicted by AI-ECG.

conclusionsAI-ECG demonstrated superior diagnostic accuracy over NT-proBNP and showed promise as a clinical triage tool. It is a potentially valuable tool for identifying the origin of dyspnoea in emergency settings and supporting decision-making.

Indexed as

Artificial IntelligenceDyspneaElectrocardiographyEmergency Service, HospitalAcute DiseaseAgedBiomarkersDiagnosis, DifferentialFemaleHeart DiseasesHumansLung DiseasesMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)ElectrocardiographyHEART FAILURESimulation Training

Identifiers

PMID39353705
PMCPMC11448159

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.