Evidence map›Paper›PMID 39353685›Full record

ArticleBMJ mental health2024

Identifying postpartum depression: Using key risk factors for early detection.

Mette-Marie Zacher Kjeldsen, Kathrine Bang Madsen, Xiaoqin Liu, Merete Lund Mægbæk, Thalia Robakis, Veerle Bergink, Trine Munk-Olsen

Abstract read
In one paragraph

Article in BMJ mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mette-Marie Zacher KjeldsenNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark mmzk.ncrr@au.dk.ORCID http://orcid.org/0000-0001-7487-3427
Kathrine Bang MadsenNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
Xiaoqin LiuNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-4519-1536
Merete Lund MægbækNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.
Thalia RobakisDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Veerle BerginkDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Trine Munk-OlsenNational Centre for Register-based Research, Aarhus University, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersonal and family history of psychiatric disorders are key risk factors for postpartum depression (PPD), yet their combined contribution has been understudied.

objectiveTo examine personal and family psychiatric history, alone and combined, and their effect on absolute risk and relative risk (RR) of mild/moderate or severe PPD.

methodsIn this cohort study, we used data from 142 064 childbirths with PPD screenings from 2015 to 2021 merged with population registers. Exposures were personal and family psychiatric history defined as a psychiatric hospital contact or psychotropic prescription fills by index mothers and their parents prior to delivery. Outcomes were mild/moderate PPD (Edinburgh Postnatal Depression Scale, cut-off: ≥11 within 12 weeks post partum) and severe PPD (antidepressant fill or depression diagnosis within 6 months post partum). We calculated absolute risks and RRs using Poisson regression models adjusted for parity, education, maternal age, and calendar year.

findingsOf the 142 064 participants, 23.4% had no psychiatric history, 47.4% had only family history, 6.0% had only personal history, and 23.2% had both. The latter group had the highest risk of PPD: absolute risk of mild/moderate PPD was 11.7% (95% CI 11.5%; 11.8%), and adjusted RR: 2.35 (95% CI 2.22; 2.49). Alone, personal psychiatric history was the most potent risk factor. Dose-response relationship based on severity of personal and family psychiatric history was found. DISCUSSION: Our study documents a substantial association between personal and family psychiatric history and PPD risk. CLINICAL IMPLICATIONS: Evaluating combinations of risk factors is important to improve risk assessment.

Indexed as

Depression, PostpartumAdultCohort StudiesEarly DiagnosisFemaleHumansMothersPregnancyRisk FactorsYoung AdultDepressionPSYCHIATRY

Identifiers

PMID39353685
PMCPMC11448151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.