Evidence map›Paper›PMID 39353426›Full record

ArticleCurrent biology : CB2024

Regulation of outer kinetochore assembly during meiosis I and II by CENP-A and KNL-2/M18BP1 in C. elegans oocytes.

Laura Bellutti, Nicolas Macaisne, Layla El Mossadeq, Thadshagine Ganeswaran, Julie C Canman, Julien Dumont

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura BelluttiUniversité Paris Cité, CNRS, Institut Jacques Monod, 75013 Paris, France.
Nicolas MacaisneUniversité Paris Cité, CNRS, Institut Jacques Monod, 75013 Paris, France.
Layla El MossadeqUniversité Paris Cité, CNRS, Institut Jacques Monod, 75013 Paris, France.
Thadshagine GaneswaranUniversité Paris Cité, CNRS, Institut Jacques Monod, 75013 Paris, France.
Julie C CanmanColumbia University, Irving Medical Center, Department of Pathology and Cell Biology, New York, NY 10032, USA.
Julien DumontUniversité Paris Cité, CNRS, Institut Jacques Monod, 75013 Paris, France. Electronic address: julien.dumont@ijm.fr.

Funding

Cell type-variation of cytokinesisR01GM117407 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2016 to 2023
$2.9M
Probing the spatiotemporal regulation of cell divisionR01GM130764 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CANMAN, JULIE C · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM117407NIGMS NIH HHS R01 GM130764
6 · The paper itself

Abstract

During cell division, chromosomes build kinetochores that attach to spindle microtubules. Kinetochores usually form at the centromeres, which contain CENP-A nucleosomes. The outer kinetochore, which is the core attachment site for microtubules, is composed of the KMN network (Knl1c, Mis12c, and Ndc80c complexes) and is recruited downstream of CENP-A and its partner CENP-C. In C. elegans oocytes, kinetochores have been suggested to form independently of CENP-A nucleosomes. Yet kinetochore formation requires CENP-C, which acts in parallel to the nucleoporin MEL-28

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCentromere Protein AKinetochoresMeiosisOocytesAnimalsChromosomal Proteins, Non-HistoneChromosome SegregationDNA-Binding ProteinsFemaleNuclear Pore Complex ProteinsCaenorhabditis elegans ProteinsCentromere Protein Acentromere protein CChromosomal Proteins, Non-HistoneDNA-Binding Proteinsmel-28 protein, C elegansNuclear Pore Complex ProteinsCENP-ACENP-Ccentromerechromosome segregationholocentrickinetochoremicrotubuleoocyte meiosis

Identifiers

PMID39353426
PMCPMC11537844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.