Evidence map›Paper›PMID 39353158›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Assessing Long-Term Quality of Life Concerns Through Survivorship Clinic in Head and Neck Cancer Patients.

Andrew Yousef, Ariadne Nichol, Bao Luu, Carie Montesa, Celia Ramsey, Philipp Verpukhovskiy, Liza Blumenfeld, Kristen Linnemeyer-Risser, Theresa Guo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Quality of life with anophthalmia: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
  2. Responsiveness and clinical utility of patient-reported outcome instruments in head and neck cancer: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew YousefDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.ORCID http://orcid.org/0000-0002-3126-1655
Ariadne NicholDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Bao LuuDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Carie MontesaDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Celia RamseyDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Philipp VerpukhovskiyDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Liza BlumenfeldDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Kristen Linnemeyer-RisserDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.
Theresa GuoDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Diego, California, USA.

Funding

UC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4M
Otolaryngology Training in Immunology, Virology and Molecular BiologyR25DC020173 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joseph A Califano · 2022 to 2026
$1.4M
NCATS NIH HHS KL2 TR001444NIDCD NIH HHS R25 DC020173
6 · The paper itself

Abstract

objectiveTo characterize the concerns of head and neck cancer (HNC) patients and discern changes in quality-of-life (QoL) during long-term follow-up. STUDY

designRetrospective review.

settingSurvivorship clinic at a tertiary academic center.

methodsA retrospective review was conducted on HNC patients seen in our survivorship clinic between 1/2020 and 1/2024 using the University of Washington Quality of Life (UW-QOL) Questionnaire.

resultsThree hundred and forty-two patients were seen for 914 encounters. Patients were divided into 4 groups: pretreatment (n = 326), 0 to 12 months posttreatment (n = 247), 1 to 3 years posttreatment (n = 248), and more than 3 years posttreatment (n = 64). The average follow-up after treatment was 459 days (range: 0-5.2 years). Multivariable analysis revealed significant improvements in overall QoL, health-related QoL, social-emotional composite scores, activity, anxiety, appearance, chewing, mood, pain, speech, and recreation at more than 1-year posttreatment compared to less than 1-year posttreatment. However, declines were noted in saliva and taste scores. No differences in scores were observed between patients 1 to 3 years posttreatment and those >3 years posttreatment. At all timepoints before and after treatment, top concerns were pain, activity, and swallowing. Patients with oral cancer followed for more than 1-year posttreatment had worse scores in appearance, chewing, pain, and speech compared to those with oropharyngeal cancer.

conclusionsUnderstanding the evolving concerns of HNC patients is imperative for enhancing care. Most QoL domains improve at 1-year posttreatment except for saliva, taste, swallowing, and shoulder function. QoL scores stabilize after 1-year post-treatment. Pain, activity, and swallowing remain the top concerns at all time points.

Indexed as

Cancer SurvivorsHead and Neck NeoplasmsQuality of LifeAcademic Medical CentersAgedCaliforniaCancer PainDeglutition DisordersFemaleFunctional StatusHumansMaleMiddle AgedMultivariate AnalysisRetrospective StudiesSocial Behaviorhead and neck cancersurvivorshipUW‐QOL, quality of life

Identifiers

PMID39353158
PMCPMC11698637

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.