Evidence map›Paper›PMID 39352564›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

The relationship between nutritional status and prognosis in advanced gastrointestinal cancer patients in palliative care: a prospective cohort study.

Ting Mao, Janelle Yorke, Xiaoju Zhang, Yan Shi, Jingyi Wang, Xiaoqian Kong, Katherine Ka Wai Lam, Qi Liu, Funa Yang, Ka Yan Ho

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ting Mao *School of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.ORCID http://orcid.org/0000-0001-7575-450X
Janelle YorkeSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Xiaoju Zhang *Department of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Yan ShiSchool of Medicine, Tongji University, Shanghai, China.
Jingyi WangSchool of Medicine, Tongji University, Shanghai, China.
Xiaoqian KongSchool of Medicine, Tongji University, Shanghai, China.
Katherine Ka Wai LamSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Qi LiuSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Funa YangSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Ka Yan HoSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China. kyeva.ho@polyu.edu.hk.ORCID http://orcid.org/0000-0003-3953-9065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to determine the nutritional status and its prognostic effect on the survival of patients with advanced gastrointestinal cancer.

methodsA prospective cohort study design was conducted in a tertiary hospital in Shanghai, China. The study consisted of 202 advanced gastrointestinal (GI) cancer patients from a palliative care unit. The following data were collected from the patients: biochemical indicators, i.e., anemia (hemoglobin levels), albumin, pre-albumin, C-reactive protein (CRP), and anthropometric parameters, i.e., body mass index (BMI), nutritional status by Patient-Generated Subjective Global Assessment (PG-SGA), and performance status by Karnofsky Performance Status (KPS). Severe malnutrition was confirmed with the PG-SGA score of ≥ 9. Kaplan-Meier survival analysis and the log-rank test were used to calculate overall survival (OS). The effect of nutritional status on survival was performed by Cox regression analysis.

resultsSevere malnutrition was found in 71.3% of patients according to the cutoff of the PG-SGA. PG-SGA score ≥ 9, albumin level < 35 g/L, and CRP level ≥ 10 mg/L predicted shortened life expectancy. Multivariate Cox regression analysis results showed that the PG-SGA score ≥ 9 and the albumin level < 35 g/L were predictive of OS.

conclusionOur data support that severe malnutrition is a predictor for OS in patients with advanced GI cancer. Information on nutritional status should be considered to individualize palliative care plan for these patients, and hence improve their quality of life.

Indexed as

Gastrointestinal NeoplasmsMalnutritionNutritional StatusPalliative CareAdultAgedAged, 80 and overChinaCohort StudiesC-Reactive ProteinFemaleHumansKaplan-Meier EstimateKarnofsky Performance StatusMaleMiddle AgedC-Reactive ProteinAdvanced cancerNutritional statusPG-SGAPrognosisSurvival

Identifiers

PMID39352564

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.