Evidence map›Paper›PMID 39352516›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Quality of life issues in patients with ductal carcinoma in situ: a systematic review.

Thenugaa Rajeswaran, Milena Gojsevic, Adrian Wai Chan, Henry C Y Wong, Shing Fung Lee, Rhys Bernard, Gustavo Nader Marta, Katarzyna Pogoda, Jennifer Y Y Kwan, Olivia Kuszaj and 13 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Thenugaa RajeswaranOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Milena GojsevicOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Adrian Wai ChanOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Henry C Y WongDepartment of Oncology, Princess Margaret Hospital, Hospital Authority, Kowloon, Hong Kong.
Shing Fung LeeDepartment of Clinical Oncology, Tuen Mun Hospital, Hospital Authority, Tuen Mun, Hong Kong.
Rhys BernardFaculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Gustavo Nader MartaDepartment of Radiation Oncology, Hospital Sírio-Libanês, Sao Paulo, Brazil.
Katarzyna PogodaDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
Jennifer Y Y KwanRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Canada.
Olivia KuszajOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Marley DayOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Tara BehroozianMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Eveline M A BleikerNetherlands Cancer Institute, Amsterdam, the Netherlands.
Cindy WongUnion Oncology Centre, Kowloon, Hong Kong.
Yuichiro KikawaDepartment of Breast Surgery, Kansai Medical University Hospital, Hirakata, Japan.
Kaori TaneDepartment of Breast Surgery, Hyogo Cancer Center, Hyogo, Japan.
Galina VelikovaLeeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Yiola MarcouDepartment of Medical Oncology, Bank of Cyprus Oncology Centre, Nicosia, Cyprus.
Vesna Bjelic-RadisicBreast Unit, Helios University Hospital Wuppertal, University Witten-Herdecke, Wuppertal, Germany.
Irene KaramOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Muna Al-KhaifiOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Samantha K F KennedyOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Edward ChowOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. edward.chow@sunnybrook.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDuctal carcinoma in situ (DCIS) of the breast is one of the most common pre-invasive cancers diagnosed in women. Quality of life (QoL) is extremely important to assess in studies including these patients due to the favorable prognosis of the disease. The primary objective of this systematic review was to compile a comprehensive list of QoL issues, all existing QoL assessment tools, and patient-reported outcome measures used to assess DCIS.

methodsA search was conducted on Ovid MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases from inception to August 2023, using keywords such as "ductal carcinoma in-situ", "quality of life", and "patient-reported outcomes." QoL issues and QoL tools in primary research studies were extracted.

resultsA total of 67 articles identified issues pertaining to patients with DCIS spanning physical, functional, and psychosocial QoL domains. Physical and functional issues observed in patients included pain, fatigue, and impaired sexual functioning. Psychosocial issues such as anxiety, depression, and confusion about one's disease were also common. QoL tools included those that assessed general QoL, breast cancer-specific tools, and issue-specific questionnaires.

conclusionThe current instruments available to assess QoL in patients with DCIS do not comprehensively capture the issues that are pertinent to patients. Thus, the modification of existing tools or the creation of a DCIS-specific QoL tool is recommended to ensure that future research will be sensitive towards challenges faced by patients with DCIS.

Indexed as

Breast NeoplasmsCarcinoma, Intraductal, NoninfiltratingPatient Reported Outcome MeasuresQuality of LifeFemaleHumansBreastDuctal carcinoma in situPatient-reported outcomePre-invasive cancerQuality of lifeSystematic review

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.