Evidence map›Paper›PMID 39352473›Full record

ArticleAnalytical and bioanalytical chemistry2024

Raman spectroscopy of large extracellular vesicles derived from human microvascular endothelial cells to detect benzo[a]pyrene exposure.

Geetika Raizada, Benjamin Brunel, Joan Guillouzouic, Kelly Aubertin, Shinsuke Shigeto, Yuka Nishigaki, Eric Lesniewska, Eric Le Ferrec, Wilfrid Boireau, Céline Elie-Caille

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Geetika RaizadaUniversité de Franche-Comté, CNRS, Institut FEMTO-ST, 25000, Besançon, France.
Benjamin BrunelUniversité de Franche-Comté, CNRS, Institut FEMTO-ST, 25000, Besançon, France. benjamin.brunel@univ-fcomte.fr.ORCID http://orcid.org/0000-0003-2858-5074
Joan GuillouzouicUniv Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé Environnement et Travail), UMR_S 1085, 35000, Rennes, France.
Kelly AubertinUniversité Paris Cité, MSC, CNRS, IVETh Expertise Facility, 45, Rue Des Saints-Pères, 75006, Paris, France.
Shinsuke ShigetoDepartment of Chemistry, Graduate School of Science and Technology, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.
Yuka NishigakiDepartment of Chemistry, Graduate School of Science and Technology, Kwansei Gakuin University, 1 Gakuen Uegahara, Sanda, Hyogo, 669-1330, Japan.
Eric LesniewskaICB UMR 6303, CNRS, University of Bourgogne Franche-Comté, 21078, Dijon, France.
Eric Le FerrecUniv Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé Environnement et Travail), UMR_S 1085, 35000, Rennes, France.
Wilfrid BoireauUniversité de Franche-Comté, CNRS, Institut FEMTO-ST, 25000, Besançon, France.
Céline Elie-CailleUniversité de Franche-Comté, CNRS, Institut FEMTO-ST, 25000, Besançon, France.

Funding

Agence Nationale de la Recherche ANR-17-EURE-0002Agence Nationale de la Recherche ANR-18-IDEX-0001Agence Nationale de la Recherche ANR-22-AIBB-0002Agence Nationale de la Recherche R23137NNBpifrance DOS0154423/00Bpifrance DOS0154424/00Bpifrance DOS0154426/00Bpifrance DOS0154427/00Région Ile de France DIM BioConvSRégion Ile de France DOS0154423/00Région Ile de France DOS0154424/00Région Ile de France DOS0154426/00Région Ile de France DOS0154427/00Région Ile de France SESAME 2019 - IVETh (EX047011)
6 · The paper itself

Abstract

Extracellular vesicles (EVs) have shown great potential as biomarkers since they reflect the physio-pathological status of the producing cell. In the context of cytotoxicity, it has been found that exposing cells to toxicants leads to changes in protein expression and the cargo of the EVs they produce. Here, we studied large extracellular vesicles (lEVs) derived from human microvascular endothelial cells (HMEC-1) to detect the modifications induced by cell exposure to benzo[a]pyrene (B[a]P). We used a custom CaF

Indexed as

Benzo(a)pyreneEndothelial CellsExtracellular VesiclesSpectrum Analysis, RamanCell LineHumansMicroscopy, Atomic ForceSupport Vector MachineSurface Plasmon ResonanceBenzo(a)pyreneAFMExtracellular vesiclesMachine learningRaman spectroscopySPRiTERS

Identifiers

PMID39352473

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.