Evidence map›Paper›PMID 39352173›Full record

ArticleInternational journal of methods in psychiatric research2024

Design of a multicenter randomized controlled trial of a post-discharge suicide prevention intervention for high-risk psychiatric inpatients: The Veterans Coordinated Community Care Study.

Lauren M Weinstock, Todd M Bishop, Mark S Bauer, Jeffrey Benware, Robert M Bossarte, John Bradley, Steven K Dobscha, Jessica Gibbs, Sarah M Gildea, Hannah Graves and 16 more

2 registry-linked trialsAbstract readClinical Trial Protocol
In one paragraph

Article in International journal of methods in psychiatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05272176 nacompletednot on this map

Targeted Intensive Case Management of Veterans at Risk of Suicide Post Inpatient Hospitalization

TypeinterventionalSponsorBrown UniversityRan2022 to 2026Enrolled850ConditionsSuicideArmsCoping Long Term with Active Suicide Program (CLASP)
NCT07404787 narecruitingnot on this mapstarted 2026, after this paper: background citation

SAFEGUARD Phase 2 Pathfinding Study

TypeinterventionalSponsorUniformed Services University of the Health SciencesRan2026 to 2029Enrolled1,500ConditionsSuicide, Suicide AttemptArmsPathfinding, Treatment As Usual (TAU)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Lauren M WeinstockDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Todd M BishopCenter of Excellence for Suicide Prevention, Canandaigua VA Medical Center, Canandaigua, New York, USA.
Mark S BauerDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Jeffrey BenwareVA St. Louis Healthcare System, St. Louis, Missouri, USA.
Robert M BossarteCenter of Excellence for Suicide Prevention, Canandaigua VA Medical Center, Canandaigua, New York, USA.
John BradleyDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Steven K DobschaVA Center to Improve Veteran Involvement in Care (CIVIC), Portland, Oregon, USA.
Jessica GibbsTennessee Valley Healthcare System, Nashville, Tennessee, USA.
Sarah M GildeaDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
Hannah GravesDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Gretchen HaasVA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA.
Samuel HouseDepartment of Psychiatry, Baptist Health-UAMS Medical Education Program, North Little Rock, Arkansas, USA.
Chris J KennedyDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Sara J LandesBehavioral Health Quality Enhancement Research Initiative (QUERI), Central Arkansas Veterans Healthcare System, North Little Rock, Arkansas, USA.
Howard LiuCenter of Excellence for Suicide Prevention, Canandaigua VA Medical Center, Canandaigua, New York, USA.
Alex LuedtkeDepartment of Statistics, University of Washington, Seattle, Washington, USA.
Brian P MarxNational Center for PTSD, VA Boston Healthcare System, Boston, Massachusetts, USA.
Aletha MillerVA North Texas Healthcare System, Dallas, Texas, USA.
Matthew K NockDepartment of Psychology, Harvard University, Cambridge, Massachusetts, USA.
Richard R OwenPsychiatric Research Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Wilfred R PigeonCenter of Excellence for Suicide Prevention, Canandaigua VA Medical Center, Canandaigua, New York, USA.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
Alejandro Santiago-ColonVA North Texas Healthcare System, Dallas, Texas, USA.
Geetha ShivakumarVA North Texas Healthcare System, Dallas, Texas, USA.
Snezana UrosevicMinneapolis VA Healthcare System, Minneapolis, Minnesota, USA.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-4831-2305

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
Department of Veterans Affairs Quality Enhancement Research Initiative EBP 22-104Department of Veterans Affairs Quality Enhancement Research Initiative PII 18-195Department of Veterans Affairs Quality Enhancement Research Initiative QUE 20-026National Center for PTSD, U.S. Department of Veterans Affairs 36C24122P0883NCATS NIH HHS UL1 TR003107VA Boston Healthcare System 36C24122P0883Warren Alpert Foundation
6 · The paper itself

Abstract

backgroundThe period after psychiatric hospital discharge is one of elevated risk for suicide-related behaviors (SRBs). Post-discharge clinical outreach, although potentially effective in preventing SRBs, would be more cost-effective if targeted at high-risk patients. To this end, a machine learning model was developed to predict post-discharge suicides among Veterans Health Administration (VHA) psychiatric inpatients and target a high-risk preventive intervention.

methodsThe Veterans Coordinated Community Care (3C) Study is a multicenter randomized controlled trial using this model to identify high-risk VHA psychiatric inpatients (n = 850) randomized with equal allocation to either the Coping Long Term with Active Suicide Program (CLASP) post-discharge clinical outreach intervention or treatment-as-usual (TAU). The primary outcome is SRBs over a 6-month follow-up. We will estimate average treatment effects adjusted for loss to follow-up and investigate the possibility of heterogeneity of treatment effects.

resultsRecruitment is underway and will end September 2024. Six-month follow-up will end and analysis will begin in Summer 2025.

conclusionResults will provide information about the effectiveness of CLASP versus TAU in reducing post-discharge SRBs and provide guidance to VHA clinicians and policymakers about the implications of targeted use of CLASP among high-risk psychiatric inpatients in the months after hospital discharge. CLINICAL TRIALS REGISTRATION: ClinicalTrials.Gov identifier: NCT05272176 (https://www. CLINICALTRIALS: gov/ct2/show/NCT05272176).

Indexed as

InpatientsPatient DischargeSuicide PreventionVeteransAdultFemaleFollow-Up StudiesHumansMaleMental DisordersMiddle AgedUnited StatesUnited States Department of Veterans Affairsbehaviorclinical trialssuicide

Identifiers

PMID39352173
PMCPMC11443605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.