Evidence map›Paper›PMID 39352038›Full record

ArticlePediatrics2024

Low-Level, Early Life Lead Exposure and School Behavior.

Ron Shadbegian, Linda Bui, Heather Klemick, Rebecca Margolit-Chan, Anh Hoang, Dennis Guignet

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ron ShadbegianAppalachian State University, Boone, North Carolina.
Linda BuiBrandeis University, Waltham, Massachusetts.
Heather KlemickUS Environmental Protection Agency, National Center for Environmental Economics, Washington, District of Columbia.
Rebecca Margolit-ChanCornell University, Ithaca, New York.
Anh HoangUniversity of Notre Dame, Notre Dame, Indiana.
Dennis GuignetAppalachian State University, Boone, North Carolina.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

objectivesTo measure how early childhood exposure to lead affects school behavior from third to eighth grade, measured by the number and days of total school suspensions and out-of-school suspensions (OSS).

methodsWe estimate Poisson models using a cohort of 284 701 students with school records from 2006-2008 in North Carolina. We adjust for demographic and socioeconomic variables and school-grade-year cohort effects, and use coarsened exact matching to ensure similar characteristics across children with blood lead levels (BLLs) 2-10 μg/dL and children in the reference group with BLLs ≤1 μg/dL.

resultsBLLs ≥3 µg/dL are positively and significantly associated with all school suspension measures for sixth through eighth graders. The estimated effects on OSS for sixth through eighth graders are larger than the effects on total suspensions. For example, students with BLL = 3 µg/dL receive OSS 16% (95% confidence interval 3.6%-30%) more often and for 22% (95% confidence interval 7.3%-33%) more days than students with BLL ≤1 µg/dL. For third through fifth grade students, we only find a significant effect of lead exposure on suspensions at relatively high BLLs of 8-10 µg/dL.

conclusionsOur analysis demonstrates that BLL has significant adverse effects on third through eighth grade students' behavior, including at levels below the current Centers for Disease Control and Prevention's blood lead reference value of 3.5 μg/dL. We find that the adverse effects of lead are most strongly associated with more severe disruptive behavior in sixth through eighth graders, as measured by OSS. Our results underscore the long-term benefits of preventing early childhood exposure to lead.

Indexed as

Environmental ExposureLeadAdolescentChildChild BehaviorCohort StudiesFemaleHumansLead PoisoningMaleNorth CarolinaSchoolsStudentsLead

Identifiers

PMID39352038
PMCPMC11552067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.