Evidence map›Paper›PMID 39351810›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2024

Improved outcomes with leadless vs. single-chamber transvenous pacemaker in haemodialysis patients.

Alexandre Panico, Adrien Flahault, Francis Guillemin, Emilie Varlet, Cécile Couchoud, Marc Bauwens, Eloi Marijon, Stéphane Roueff, Hélène Lazareth

Abstract readComparative Study
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [Leadless cardiac pacemaker : Overview, tips, and tricks].Herzschrittmachertherapie & Elektrophysiologie · 2025
    Review
  5. Micra leadless pacemaker revisions: incidence, characteristics, and outcomes from a multicentre French cohort.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  6. Comparison of readmission outcomes and complications between leadless and traditional transvenous pacemakers in older adults: a nationwide readmission analysis of 49852 admission events.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandre PanicoDepartment of Nephrology, Centre Hospitalier Régional Universitaire de Nancy, Rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France.ORCID 0009-0003-2277-2183
Adrien FlahaultDepartment of Nephrology, Centre Hospitalier Régional Universitaire de Nancy, Rue du Morvan, 54500 Vandoeuvre-Les-Nancy, France.ORCID 0000-0003-4632-6332
Francis GuilleminCentre Hospitalier Régional Universitaire de Nancy, Inserm, Université de Lorraine, Clinical Investigation Centre-Clinical Epidemiology, Nancy, France.ORCID 0000-0002-9860-7024
Emilie VarletDepartment of Cardiology, APHP, Hôpital Européen Georges Pompidou, Paris, France.
Cécile CouchoudREIN Registry, Agence de la biomédecine, Saint Denis La Plaine, France.ORCID 0000-0002-9273-660X
Marc BauwensREIN Registry, Agence de la biomédecine, Saint Denis La Plaine, France.
Eloi MarijonDepartment of Cardiology, APHP, Hôpital Européen Georges Pompidou, Paris, France.ORCID 0000-0001-7227-3428
Stéphane RoueffDepartment of Nephrology, APHP, Hôpital Européen Georges Pompidou, Paris, France.
Hélène LazarethFaculté de Médecine, Université Paris Cité, Paris, France.ORCID 0000-0002-1500-3736

Funding

Agence de la biomédecineAgence Régionale de Santé
6 · The paper itself

Abstract

aimsCardiac conduction disorders are common in haemodialysis patients, with a relatively high rate of pacemaker implantations. Pacemaker-related complications, especially lead infections and central venous stenosis, pose significant challenges in this population. This study aims to compare single-chamber leadless pacemaker to single-chamber transvenous pacemakers in terms of survival and related complications in haemodialysis patients. METHODS AND

resultsThis retrospective study included adult haemodialysis patients who received a first single-chamber transvenous or leadless pacemaker between January 2017 and December 2020. Data were obtained from the French national REIN registry matched to the national health databases (Système National des Données de Santé). Propensity score matching was used to balance baseline characteristics. Survival and complications were compared between groups by Cox regression and by competitive risk models, respectively. One hundred and seventy-eight patients were included after propensity score matching, with 89 patients in each group. The median follow-up time was 24 (range 7-37) months. Leadless pacemakers were associated with significantly lower all-cause mortality rates compared to transvenous pacemakers [hazard ratio (HR) = 0.68, 95% confidence interval (CI) (0.47-0.99)]. Device-related infections are significantly lower with leadless pacemakers throughout the follow-up period (HR 0.43, 95% CI 0.21-0.86). Leadless pacemaker recipients also required fewer vascular access interventions [odds ratio 0.53, 95% CI (0.33-0.68)] on arteriovenous fistula.

conclusionWith the limitations of its observational design, this study suggests that leadless pacemakers are associated with a lower rate of complications and better survival as compared with transvenous VVI pacemakers in haemodialysis patients, supporting to consider their preferential use in this population.

Indexed as

Pacemaker, ArtificialRenal DialysisAgedAged, 80 and overArrhythmias, CardiacCardiac Pacing, ArtificialEquipment DesignFemaleFranceHumansMaleMiddle AgedPropensity ScoreRegistriesRetrospective StudiesTreatment OutcomeComplicationsHaemodialysisLeadless pacemakersSingle-chamber transvenous pacemakersSurvivalVascular access for haemodialysis

Identifiers

PMID39351810
PMCPMC11542626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.