Evidence map›Paper›PMID 39351695›Full record

ArticleAnnals of medicine2024

Clinical characterization and founder effect analysis in Chinese amyotrophic lateral sclerosis patients with

Pei-Shan Wang, Xin-Xia Yang, Qiao Wei, Yong-Ting Lv, Zhi-Ying Wu, Hong-Fu Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pei-Shan WangDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xin-Xia YangDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qiao WeiDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yong-Ting LvDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhi-Ying WuDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Hong-Fu LiDepartment of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0002-2203-0046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn the Asian population,

methodsA total of 103 sporadic ALS (SALS) and 11 familial ALS (FALS) probands were included and variants were screened by whole exome sequencing. Functional analyses were performed on fibroblasts derived from patients with

resultsA total of 25

conclusionsOur study expanded the understanding of the genotype-phenotype correlation of ALS with

Indexed as

Amyotrophic Lateral SclerosisFounder EffectSuperoxide Dismutase-1AdultAgedAge of OnsetChinaEast Asian PeopleExome SequencingFemaleGenetic Association StudiesHaplotypesHumansMaleMiddle AgedMutationSOD1 protein, humanSuperoxide Dismutase-1Amyotrophic lateral sclerosisChinesecommon variantsfounder effectSOD1SOD1 aggregation

Identifiers

PMID39351695
PMCPMC11445911

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.