Evidence map›Paper›PMID 39351623›Full record

Trial reportScience progress

Appropriate dose of tranexamic acid in the topical treatment of anterior epistaxis, 500 mg vs 1000 mg: A double-blind randomized controlled trial.

Cüneyt Arikan, Pınar Yeşim Akyol

Abstract readRandomized Controlled TrialClinical Trial, Phase IV
In one paragraph

Trial report in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Tranexamic acid solution for nosebleeds.Canadian family physician Medecin de famille canadien · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cüneyt ArikanDepartment of Emergency Medicine, İzmir Ataturk Training and Research Hospital, Izmir, Turkey.ORCID 0000-0001-6823-5357
Pınar Yeşim AkyolDepartment of Emergency Medicine, İzmir Ataturk Training and Research Hospital, Izmir, Turkey.ORCID 0000-0003-2477-1443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsPatients with epistaxis typically visit the emergency department for initial treatment. According to recent studies, tranexamic acid (TXA) is effective in the treatment of epistaxis. This study compared the therapeutic superiority of saline to that of 500 and 1000 mg doses of topical TXA for the treatment of anterior epistaxis.

Indexed as

Administration, TopicalAntifibrinolytic AgentsEpistaxisTranexamic AcidAdultAgedDose-Response Relationship, DrugDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment OutcomeAntifibrinolytic AgentsTranexamic AcidAnterior epistaxisemergency medicinetopicaltranexamic acidtreatment

Identifiers

PMID39351623
PMCPMC11475088

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.