Evidence map›Paper›PMID 39351160›Full record

ReviewBiomaterials translational2024

Decellularised extracellular matrix-based injectable hydrogels for tissue engineering applications.

Wan-Ying Guo, Wei-Huang Wang, Pei-Yao Xu, Ranjith Kumar Kankala, Ai-Zheng Chen

Abstract readReview
In one paragraph

Review in Biomaterials translational, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wan-Ying GuoInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Wei-Huang WangInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Pei-Yao XuInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Ranjith Kumar KankalaInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian Province, China.
Ai-Zheng ChenInstitute of Biomaterials and Tissue Engineering, Huaqiao University, Xiamen, Fujian Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decellularised extracellular matrix (dECM) is a biomaterial derived from natural tissues that has attracted considerable attention from tissue engineering researchers due to its exceptional biocompatibility and malleability attributes. These advantageous properties often facilitate natural cell infiltration and tissue reconstruction for regenerative medicine. Due to their excellent fluidity, the injectable hydrogels can be administered in a liquid state and subsequently formed into a gel state in vivo, stabilising the target area and serving in a variety of ways, such as support, repair, and drug release functions. Thus, dECM-based injectable hydrogels have broad prospects for application in complex organ structures and various tissue injury models. This review focuses on exploring research advances in dECM-based injectable hydrogels, primarily focusing on the applications and prospects of dECM hydrogels in tissue engineering. Initially, the recent developments of the dECM-based injectable hydrogels are explained, summarising the different preparation methods with the evaluation of injectable hydrogel properties. Furthermore, some specific examples of the applicability of dECM-based injectable hydrogels are presented. Finally, we summarise the article with interesting prospects and challenges of dECM-based injectable hydrogels, providing insights into the development of these composites in tissue engineering and regenerative medicine.

Indexed as

decellularisation methodsdecellularised extracellular matrixinjectable hydrogelstissue engineering

Identifiers

PMID39351160
PMCPMC11438603

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.