Evidence map›Paper›PMID 39351150›Full record

ArticleFrontiers in veterinary science2024

Effect of coated-benzoic acid on growth performance, immunity, and intestinal functions in weaned pigs challenged by enterotoxigenic

Jiawen Qi, Bing Yu, Youjun Hu, Yuheng Luo, Ping Zheng, Xiangbing Mao, Jie Yu, Xiaonan Zhao, Taiqian He, Hui Yan and 2 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jiawen QiInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Bing YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Youjun HuNuacid Nutrition Co., Ltd, Qingyuan, China.
Yuheng LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Ping ZhengInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Xiangbing MaoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Jie YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Xiaonan ZhaoNuacid Nutrition Co., Ltd, Qingyuan, China.
Taiqian HeNuacid Nutrition Co., Ltd, Qingyuan, China.
Hui YanInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Aimin WuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.
Jun HeInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Benzoic acid (BA) could be added to the diets of weaned pigs to prevent diarrhea due to its antibacterial function. However, BA may be absorbed or decomposed before it can reach the hindgut. This study was conducted to explore the effect of a novel coated benzoic acid (CBA) on growth performance, immunity, and intestinal barrier functions in weaned pigs upon enterotoxigenic Methods: In a 21d experiment, 32 piglets were randomly assigned to 4 treatments: (1) a basal diet (CON), (2) CON added with CBA at 3  g/kg (CBA); (3) CON and challenged by ETEC (ECON); (4) CON added with CBA at 3 g/kg and challenged by ETEC (ECON). On d 22, all piglets were euthanised to obtain samples. Results: Dietary CBA supplementation elevated the average daily gain (ADG) of the ETEC-challenged pigs ( Discussion: These results suggested a beneficial role for CBA in alleviating intestinal injury in weaned pigs following ETEC challenge. Such effects may be tightly associated with elevated immunity and improved intestinal epithelium functions and microbiota.

Indexed as

coated benzoic acidenterotoxigenic Escherichia coliimmunityintestinal epitheliumweaned pigs

Identifiers

PMID39351150
PMCPMC11439879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.