Evidence map›Paper›PMID 39350453›Full record

ReviewThe Journal of dermatology2025

Buruli ulcer: An epidemiological update from Japan.

Ryo Fukaura, Manabu Ato, Chiaki Murase, Yuji Miyamoto, Mariko Sugawara-Mikami, Toshifumi Takahashi, Yoshihiko Hoshino, Noriki Fujimoto, Masashi Akiyama, Norihisa Ishii and 1 more

Abstract readReview
In one paragraph

Review in The Journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Spatiotemporal distribution ofEmerging microbes & infections · 2025
    Article
  3. Repurposing drugs to advance the treatment of Buruli ulcer.Antimicrobial agents and chemotherapy · 2025
    Article
  4. Buruli ulcer: An epidemiological update from Japan.The Journal of dermatology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ryo FukauraDepartment of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0002-3946-7893
Manabu AtoLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Chiaki MuraseDepartment of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0001-5331-1222
Yuji MiyamotoLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Mariko Sugawara-MikamiSugawara Dermatology Clinic, Yokohama, Japan.
Toshifumi TakahashiDepartment of Dermatology, Shiga University of Medical Science, Otsu, Japan.ORCID https://orcid.org/0000-0001-6059-9092
Yoshihiko HoshinoLeprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Noriki FujimotoDepartment of Dermatology, Shiga University of Medical Science, Otsu, Japan.ORCID https://orcid.org/0000-0003-4051-0649
Masashi AkiyamaDepartment of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0001-5863-9315
Norihisa IshiiNational Sanatorium Tama Zenshoen, Tokyo, Japan.
Rie YotsuDepartment of Tropical Medicine and Infectious Disease, Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.

Funding

Japan Agency for Medical Research and DevelopmentJapan International Cooperation AgencyJapan Society for the Promotion of Science
6 · The paper itself

Abstract

Japan is one of the rare non-tropical countries with documented cases of Buruli ulcer (BU). Mycobacterium ulcerans subsp. shinshuense has been identified as the causative agent. The first report of BU in Japan dates back to 1982, with sporadic reports thereafter. Recently, the number of cases has been on the increase, and 50 cases (57.7%) are from the past decade alone, out of a total of 87 cases reported to date. Japan's well-developed healthcare facilities play a crucial role in enabling detailed investigations and providing appropriate treatment for patients, contributing to a favorable prognosis. However, the rarity of the disease results in lack of awareness among healthcare professionals, leading to frequent delays in diagnosis. This article aims to offer an updated overview of BU cases in Japan and to raise awareness of BU among dermatologists and other healthcare professionals in a non-endemic setting.

Indexed as

Buruli UlcerMycobacterium ulceransAdolescentAdultChildFemaleHumansJapanMaleMiddle AgedYoung AdultJapanesemycobacterium ulcerans subsp. shinshuensemycolactoneneglected tropical diseasetransmission

Identifiers

PMID39350453
PMCPMC11700950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.