Evidence map›Paper›PMID 39350383›Full record

ArticleThe journal of prevention of Alzheimer's disease2024

Risk of Dementia in Korean Vietnam War Veterans.

W Lee, S Lee, S-K Kang, W-J Choi

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Article in The journal of prevention of Alzheimer's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

W LeeWon-Jun Choi, M.D., MPH, Ph.D. Department of Occupational and Environmental Medicine, Gil Medical Center, Gachon University College of Medicine, 21, Namdong-daero 774beon-gil, Namdong-gu, Incheon, Republic of Korea, Postal code: 21565, E-mail: wjchoi@gachon.ac.kr, Tel: +82-32-460-8866, Fax: +82-32-460-2363.
S Lee
S-K Kang
W-J Choi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of cases of all types of dementia is increasing, and a significant increase in prevalence has been noted among veterans. Evidence of an association between dementia and exposure to chemicals such as Agent Orange from the Vietnam War is still limited, and there is a reported lack of awareness.

objectiveThis study aimed to investigate the risk of dementia among Vietnam War veterans in Korea.

designThis retrospective longitudinal study compared the incidence of dementia between Vietnam War veterans and the general population.

settingThis study used data from the nationally representative Korean Vietnam War Veterans' Health Study Cohort, a combined dataset sourced from the Ministry of Patriots and Veterans Affairs in Korea and the National Health Insurance Sharing Service database.

participantsThere were 191,272 Vietnam War veterans and 1,000,320 people of different ages, sexes, and residences. matched control in 2002. The total number of person-years were 18,543,181. MEASUREMENTS: The dementia group included participants who had visited a medical facility with any of the following ICD-10 codes in the follow-up periods: "F00 Dementia in Alzheimer's disease," "F01 Vascular dementia," "F02 Dementia in other diseases classified elsewhere," or "F03 Unspecified dementia."

resultsThe incidence rate ratio for all types of dementia was 1.16, with higher ratios observed for vascular and unspecified dementia, particularly in the younger age groups. There was a significant increase in the risk of dementia, Alzheimer's disease, vascular dementia, and unspecified dementia.

conclusionVietnam War veterans showed an increased risk for all types of dementia. These findings are hypothesized to be due to the effects of the chemicals used during the Vietnam War, which can cause a variety of neurodegenerative diseases. Further studies are warranted to investigate the potential health determinants related to the Vietnam War, focusing on the neurodegenerative effects.

Indexed as

Agent OrangeDementiaVeteransVietnam Conflict2,4,5-Trichlorophenoxyacetic Acid2,4-Dichlorophenoxyacetic AcidAdultAgedDefoliants, ChemicalFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedRepublic of Korea2,4,5-Trichlorophenoxyacetic Acid2,4-Dichlorophenoxyacetic AcidAgent OrangeDefoliants, ChemicalAgent OrangedementiaKOVECOveteransVietnam War

Identifiers

PMID39350383
PMCPMC11436388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.