Evidence map›Paper›PMID 39350186›Full record

Trial reportBMC medical informatics and decision making2024

Machine-learning-based models for the optimization of post-cervical spinal laminoplasty outpatient follow-up schedules.

Yechan Seo, Seoi Jeong, Siyoung Lee, Tae-Shin Kim, Jun-Hoe Kim, Chun Kee Chung, Chang-Hyun Lee, John M Rhee, Hyoun-Joong Kong, Chi Heon Kim

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC medical informatics and decision making, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02487901 (Randomized Controlled Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02487901 nacompletednot on this map

Randomized Controlled Trial: Comparison of Ultrasonic Osteotome and Conventional Drill Osteotome

TypeinterventionalSponsorSeoul National University HospitalRan2015 to 2018Enrolled190ConditionsArthrodesisArmsultrasonic osteotome, drill
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yechan Seo *Department of Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Seoi Jeong *Department of Transdisciplinary Medicine, Seoul National University Hospital, 101 Daehak-Ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Siyoung LeeSchool of Medicine, the Faculty of Medical Science, Newcastle University, Newcastle Upon Tyne, NE2 4HH, UK.
Tae-Shin KimDepartment of Neurosurgery, Champodonamu Hospital, 32 Baumoe-ro 35-gil, Seocho-gu, Seoul, 03080, Republic of Korea.
Jun-Hoe KimDepartment of Neurosurgery, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Chun Kee ChungDepartment of Neurosurgery, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
Chang-Hyun LeeDepartment of Neurosurgery, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.
John M RheeDepartment of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, GA, 30322, USA.
Hyoun-Joong KongDepartment of Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. gongcop7@snu.ac.kr.ORCID http://orcid.org/0000-0001-5456-4862
Chi Heon KimDepartment of Neurosurgery, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. chiheon1@snu.ac.kr.

Funding

Armed Forces Capital Hospital 800-20230466Doosan Yonkang Foundation 800-20210527Seoul National University Hospital research fund 3020230120
6 · The paper itself

Abstract

backgroundPatients undergo regular clinical follow-up after laminoplasty for cervical myelopathy. However, those whose symptoms significantly improve and remain stable do not need to conform to a regular follow-up schedule. Based on the 1-year postoperative outcomes, we aimed to use a machine-learning (ML) algorithm to predict 2-year postoperative outcomes.

methodsWe enrolled 80 patients who underwent cervical laminoplasty for cervical myelopathy. The patients' Japanese Orthopedic Association (JOA) scores (range: 0-17) were analyzed at the 1-, 3-, 6-, and 12-month postoperative timepoints to evaluate their ability to predict the 2-year postoperative outcomes. The patient acceptable symptom state (PASS) was defined as a JOA score ≥ 14.25 at 24 months postoperatively and, based on clinical outcomes recorded up to the 1-year postoperative timepoint, eight ML algorithms were developed to predict PASS status at the 24-month postoperative timepoint. The performance of each of these algorithms was evaluated, and its generalizability was assessed using a prospective internal test set.

resultsThe long short-term memory (LSTM)-based algorithm demonstrated the best performance (area under the receiver operating characteristic curve, 0.90 ± 0.13).

conclusionsThe LSTM-based algorithm accurately predicted which group was likely to achieve PASS at the 24-month postoperative timepoint. Although this study included a small number of patients with limited available clinical data, the concept of using past outcomes to predict further outcomes presented herein may provide insights for optimizing clinical schedules and efficient medical resource utilization.

trial registrationThis study was registered as a clinical trial (Clinical Trial No. NCT02487901), and the study protocol was approved by the Seoul National University Hospital Institutional Review Board (IRB No. 1505-037-670).

Indexed as

Cervical VertebraeLaminoplastyMachine LearningAdultAgedAlgorithmsFemaleHumansMaleMiddle AgedSpinal Cord DiseasesCervical vertebraLaminoplastyMachine learningOutpatient clinicPatient outcome assessmentTelemedicine

Identifiers

PMID39350186
PMCPMC11440713

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.