ArticleBMC psychiatry2024
Associations of overactive bladder (OAB) with suicidal ideation incidence and all-cause mortality among the U.S. population.
Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association of Vitamin D Levels and Mortality in Overactive Bladder: Nonlinear Dose-Response and Threshold Effect.Food science & nutrition · 2026Article
- Oxidative Balance Score and Overactive Bladder Risk in US Adults: A Negative Dose-Response Association from NHANES 2005-2018.International urogynecology journal · 2026Article
- Association between Apolipoprotein B (ApoB) and suicidal ideation: a cross-sectional study and Mendelian randomization analysis.Annals of general psychiatry · 2026Article
- Biological aging partly mediates the association between physical activity and overactive bladder: evidence from NHANES 2007-2020.Clinical epigenetics · 2026Article
- Mediating role of SII in the association between LC9 and overactive bladder.Scientific reports · 2025Article
- Association of overactive bladder with red cell distribution width to albumin ratio in American.Scientific reports · 2025Article
- Association of overactive bladder with all-cause and cardiovascular mortality in women: A propensity-matched NHANES study.BJUI compass · 2025Article
- Atherogenic Index of Plasma mediates the association between Life's Crucial 9 with overactive bladder: a secondary data analysis from NHANES.Frontiers in endocrinology · 2025Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have explored the correlation between overactive bladder (OAB) and suicidal ideation. This study aims to investigate the association between OAB and suicidal ideation, as well as the relationship between OAB and all-cause mortality among individuals with suicidal ideation.
methodsData from the 2005-2018 National Health and Nutrition Examination Survey (NHANES) were analyzed using cross-sectional and cohort study designs. Weighted multivariable logistic regression models were used to examine the association between OAB and suicidal ideation. Kaplan-Meier curves and weighted multivariable Cox proportional hazards models assessed the relationship between OAB and all-cause mortality among those with suicidal ideation. Interaction analyses on subgroups were conducted to validate the findings. Mediation analysis was performed to examine the effect of depression on the relationship between OAB and suicidal ideation.
resultsAmong 33,426 participants aged ≥ 20 years, 1,290 (3.8%) reported suicidal ideation. After adjusting for potential confounders, participants with OAB were 2.57 times more likely to have suicidal ideation (P < 0.001). Over an average follow-up of 87 months, 197 participants with suicidal ideation died. The Cox model revealed that participants with OAB had a 3.08 times higher risk of death (P = 0.006). Kaplan-Meier curves indicated higher survival rates for non-OAB participants. Mediation analysis indicates that depression significantly mediates the relationship between OAB and suicidal ideation, with a mediation proportion of 75.25% (P < 0.001).
conclusionsOAB is positively associated with the incidence of suicidal ideation and all-cause mortality among participants with suicidal ideation. Additionally, the association between OAB and suicidal ideation is mediated by depression.
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