Evidence map›Paper›PMID 39349747›Full record

ArticleCommunications biology2024

Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out mice.

Jun-Hyung Jung, Jinhong Kim, Uroos Akber, Na Young Lee, Jeong-Won Baek, Jieun Jung, Mincheol Park, Jiseung Kang, Seungje Jeon, Chul-Seung Park and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jun-Hyung Jung *School of Life Sciences, Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea.
Jinhong Kim *Department of Biomedical Science and Engineering, GIST, Gwangju, Republic of Korea.
Uroos AkberSchool of Life Sciences, Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea.
Na Young LeeSchool of Life Sciences, Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea.
Jeong-Won BaekSchool of Life Sciences, Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea.
Jieun JungDepartment of Biomedical Science and Engineering, GIST, Gwangju, Republic of Korea.
Mincheol ParkDepartment of Biomedical Science and Engineering, GIST, Gwangju, Republic of Korea.
Jiseung KangDepartment of Biomedical Science and Engineering, GIST, Gwangju, Republic of Korea.
Seungje JeonDepartment of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Chul-Seung ParkSchool of Life Sciences, Gwangju Institute Science and Technology (GIST), Gwangju, Republic of Korea. cspark@gist.ac.kr.ORCID 0000-0003-0209-1412
Tae KimDepartment of Biomedical Science and Engineering, GIST, Gwangju, Republic of Korea. tae-kim@gist.ac.kr.ORCID 0000-0003-0201-5401

Funding

Ministry of Health and Welfare (Ministry of Health, Welfare and Family Affairs) HU22C0150National Research Foundation of Korea (NRF) 2022R1A2C1005532National Research Foundation of Korea (NRF) NRF-2018M3C7A1056293
6 · The paper itself

Abstract

Energy homeostasis and sleep have a bidirectional relationship. Cereblon (CRBN) regulates energy levels by ubiquitinating the AMP-activated protein kinase(AMPK), an energy sensor. However, whether CRBN participates in sleep is unclear. Here, we examine sleep-wake patterns in Crbn

Indexed as

Adaptor Proteins, Signal TransducingHomeostasisMice, KnockoutSleepAnimalsHSP40 Heat-Shock ProteinsMaleMiceMice, Inbred C57BLSleep DeprivationUbiquitin-Protein LigasesAdaptor Proteins, Signal TransducingCrbn protein, mouseHSP40 Heat-Shock ProteinsUbiquitin-Protein Ligases

Identifiers

PMID39349747
PMCPMC11442454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.