Evidence map›Paper›PMID 39349640›Full record

ReviewDiscover oncology2024

The role of the ceRNA network mediated by lncRNA SNHG3 in the progression of cancer.

Ying Peng, Xi-Dai Long

Abstract readReview
In one paragraph

Review in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ying PengDepartment of Pathology, the First Affiliated Hospital, Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning, 530021, People's Republic of China.
Xi-Dai LongDepartment of Pathology, the Affiliated Hospital of Youjiang Medical University for Nationalities, Guangxi Zhuang Autonomous Region, Baise, 533000, People's Republic of China. sjtulongxd@ymun.edu.cn.ORCID https://orcid.org/0000-0003-0960-0689

Funding

Bose Talent Highland 2020-3-2Building Projects from the Key Laboratory of Molecular Pathology (Hepatobiliary Diseases) of Guangxi Guiweikejiaofa [2020]-17Building Projects of Guangxi Bagui Scholars 2024Clinical Key Specialty Building Project (For Pathology) of Guangxi Guiweiyifa [2022]-21Guangxi Training Program for Medical High-level Academic Leaders Guiweikejiaofa [2020]-15the Key Laboratory of Tumor Molecular Pathology of Guangxi Colleges & Universities Guijiaokeyan [2022]-10
6 · The paper itself

Abstract

backgroundLong non-coding RNAs (lncRNAs) are a distinct class of RNAs with longer than 200 base pairs that are not translated into proteins. Small Nucleolar RNA Host Gene 3 (SNHG3) is a lncRNA and frequently dysregulated in various human cancers.

objectiveThis review provides a comprehensive analysis of current research on lncRNA SNHG3, focusing on its role within the competitive endogenous RNA (ceRNA) network and its implications in cancer.

methodsA systematic literature review was conducted using PubMed up to October 2023. The search strategy included keywords such as "lncRNA SNHG3", "competitive endogenous RNA", "cancer", and related terms. Studies were selected based on relevance to SNHG3's involvement in cancer pathogenesis and progression.

resultsDisruptions in the ceRNA network involving lncRNA SNHG3 can impair normal cell growth and differentiation, significantly contributing to disease pathogenesis, particularly cancer. This review highlights SNHG3's substantial impact on various cancer processes and its potential as a diagnostic and therapeutic tool for aggressive cancers.

conclusionThe findings underscore SNHG3's pivotal role in cancer prevention, diagnosis, and treatment, laying a foundation for future research in cancer management. Insights from this review emphasize the necessity for further exploration and development of SNHG3-based diagnostic and therapeutic strategies.

Indexed as

Competitive endogenous RNAsHuman cancerLncRNA SNHG3,Long non-coding RNAPotential therapeutic target,Tumorigenesis biomarker,

Identifiers

PMID39349640
PMCPMC11442963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.