Evidence map›Paper›PMID 39349555›Full record

ArticleScientific reports2024

Therapeutic potential of histamine H

Jung Won Kwon, Kihwang Lee, Sang Wha Kim, Jisu Park, Jung Joo Hong, Jeong-Hwan Che, Seung Hyeok Seok

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jung Won Kwon *Macrophage Lab, Department of Microbiology and ImmunologyInstitute of Endemic Disease, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kihwang Lee *Department of Pediatric Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea.
Sang Wha Kim *Macrophage Lab, Department of Microbiology and ImmunologyInstitute of Endemic Disease, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jisu ParkMacrophage Lab, Department of Microbiology and ImmunologyInstitute of Endemic Disease, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jung Joo HongNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.
Jeong-Hwan CheBiomedical Center for Animal Resource Development and Institute for Experimental Animals, Seoul National University College of Medicine, Seoul, Republic of Korea. casache@snu.ac.kr.
Seung Hyeok SeokMacrophage Lab, Department of Microbiology and ImmunologyInstitute of Endemic Disease, Seoul National University College of Medicine, Seoul, Republic of Korea. lamseok@snu.ac.kr.

Funding

K-Bio Health R&D Project, Ministry of Health & Welfare, Republic of Korea HO16C0001Korea Research Institute of Bioscience and Biotechnology Research Initiative Program KGM4572323National Research Foundation of Korea RS-2024-00356146
6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a prevalent complication of diabetes, often resulting in vision loss and blindness. Existing treatments primarily aim to control blood sugar levels and inhibit angiogenesis. However, current therapies for DR, such as anti-VEGF and laser photocoagulation, are frequently invasive, and can cause adverse side effects. Consequently, there is a critical need for new preventive therapeutics to address DR more effectively. This study aimed to examine the therapeutic potential of a histamine H

Indexed as

Diabetes Mellitus, ExperimentalDiabetic RetinopathyReceptors, Histamine H4AnimalsDisease Models, AnimalHistamine AntagonistsMacrophagesMaleMiceMice, Inbred C57BLRetinaRetinal VesselsHistamine AntagonistsHrh4 protein, mouseReceptors, Histamine H4Diabetic retinopathyHistamine H4 receptorMacrophagesRetinal inflammationVascular permeability

Identifiers

PMID39349555
PMCPMC11443088

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.