Evidence map›Paper›PMID 39349508›Full record

ArticleNPJ biofilms and microbiomes2024

Preventing bacterial adhesion to skin by altering their physicochemical cell surface properties specifically.

Xavier Janvier, Severine Jansen, Charleyne Prenom, Nabiha Khodabux, Francesca Zuttion, Cécile Duclairoir-Poc, Sylvie Cupferman, Ahmad Khodr

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xavier JanvierL'Oréal Research & Innovation, Chevilly-Larue, France.ORCID http://orcid.org/0000-0002-6189-2896
Severine Jansen *L'Oréal Research & Innovation, Chevilly-Larue, France.
Charleyne Prenom *L'Oréal Research & Innovation, Chevilly-Larue, France.
Nabiha KhodabuxL'Oréal Research & Innovation, Chevilly-Larue, France.
Francesca ZuttionL'Oréal Research & Innovation, Aulnay-sous-Bois, France.
Cécile Duclairoir-PocBacterial Communication and Anti-infectious Strategies (CBSA), UR4312, Rouen-Normandy University, Evreux, France.ORCID http://orcid.org/0000-0001-8386-8769
Sylvie CupfermanL'Oréal Research & Innovation, Chevilly-Larue, France.
Ahmad KhodrL'Oréal Research & Innovation, Chevilly-Larue, France. ahmad.khodr@loreal.com.ORCID http://orcid.org/0000-0003-2065-4338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adhesion of bacteria to surfaces is associated with physicochemical and biological interactions. The present investigations provide new results about the differential adhesion levels of skin bacteria using a representative 3D skin model which mainly relies on the different physicochemical properties of the respective surfaces. Modulation of the adhesion of bacteria and thus their colonization, may occur by adjusting the physicochemical properties of the epidermal and bacterial surfaces. Lewis acid and hydrophobicity were the most strongly correlated parameters with the antiadhesion properties of the tested compounds. Modulation of physicochemical properties appears to be the primary driver of reduced Staphylococcus aureus adhesion in this study, with no significant changes observed in the expression of genes associated with classical adhesion pathways.

Indexed as

Bacterial AdhesionHydrophobic and Hydrophilic InteractionsSkinStaphylococcus aureusSurface PropertiesHumans

Identifiers

PMID39349508
PMCPMC11442763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.