Evidence map›Paper›PMID 39349492›Full record

ArticleNPJ Parkinson's disease2024

TMS-evoked potentials unveil occipital network involvement in patients diagnosed with Parkinson's disease within 5 years of inclusion.

Noa Zifman, Ofri Levy-Lamdan, Tal Hiller, Avner Thaler, Iftach Dolev, Anat Mirelman, Hilla Fogel, Mark Hallett, Inbal Maidan

Registry-linked trialAbstract read
In one paragraph

Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06963775 (Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06963775 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials (TMS-EEG)

TypeobservationalSponsorRamon Diaz-ArrastiaRan2026 to 2030Enrolled215ConditionsTraumatic Brain InjuryArmsDelphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noa ZifmanQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Ofri Levy-LamdanQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Tal HillerQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Avner ThalerLaboratory of Early Markers of Neurodegeneration (LEMON), Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Iftach DolevQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Anat MirelmanLaboratory of Early Markers of Neurodegeneration (LEMON), Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Hilla FogelQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Mark HallettQuantalX Neuroscience Ltd., Kfar Saba, Israel.
Inbal MaidanLaboratory of Early Markers of Neurodegeneration (LEMON), Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. inbalm@tlvmc.gov.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Distinguishing Parkinson's disease (PD) subgroups may be achieved by observing network responses to external stimuli. We compared TMS-evoked potential (TEP) measures from stimulation of bilateral motor cortex (M1), dorsolateral prefrontal cortex (DLPFC), and visual cortex (V1) between 62 PD patients (age: 69.9 ± 7.5) and 76 healthy controls (age: 69.2 ± 4.3) using a TMS-EEG protocol. TEP measures were analyzed using two-way ANCOVA adjusted for MOCA. PD patients were divided into tremor dominant (TD), non-tremor dominant (NTD) and rapid disease progression (RDP) subgroups. PD patients showed lower wide-waveform adherence (wWFA) (p = 0.025) and interhemispheric connectivity (IHC

Identifiers

PMID39349492
PMCPMC11443052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.